Dissection of gene expression datasets into clinically relevant interaction signatures via high-dimensional correlation maximization
Identification of clinically relevant gene expression signatures for cancer stratification remains challenging. Here, the authors introduce a flexible nonlinear signal superposition model that enables dissection of large gene expression data sets into signatures and extraction of gene interactions.
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Main Authors: | Michael Grau, Georg Lenz, Peter Lenz |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
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Online Access: | https://doaj.org/article/e6122c78f3584f9387082cbd4ab6e29f |
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