Clinical Significance of Diabetic Dermatopathy

Piyu Parth Naik,1 Syed Nadir Farrukh2 1Department of Dermatology, Saudi-German Hospitals & Clinics, Dubai, United Arab Emirates; 2Department of Internal Medicine, Adam-Vital Hospital, Dubai, United Arab EmiratesCorrespondence: Piyu Parth NaikDepartment of Dermatology, Saudi-German Hospitals...

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Autores principales:	Naik PP, Farrukh SN
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	diabetic dermopathy diabetes mellitus pretibial patches cutaneous lesions in diabetics microvascular disease Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/e618e7f8bb8441179999e52b6f56e729
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spelling	oai:doaj.org-article:e618e7f8bb8441179999e52b6f56e7292021-12-02T15:10:21ZClinical Significance of Diabetic Dermatopathy1178-7007https://doaj.org/article/e618e7f8bb8441179999e52b6f56e7292020-12-01T00:00:00Zhttps://www.dovepress.com/clinical-significance-of-diabetic-dermatopathy-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Piyu Parth Naik,1 Syed Nadir Farrukh2 1Department of Dermatology, Saudi-German Hospitals & Clinics, Dubai, United Arab Emirates; 2Department of Internal Medicine, Adam-Vital Hospital, Dubai, United Arab EmiratesCorrespondence: Piyu Parth NaikDepartment of Dermatology, Saudi-German Hospitals & Clinics, Hessa Street 331 West, Al Barsha 3, Exit 36 Sheikh Zayed Road, Opposite of American School, Dubai, United Arab EmiratesTel +971562173323Email drpiyu85@gmail.comAbstract: Diabetic dermopathy is a cutaneous manifestation commonly seen in diabetes patients and was initially described by Melin in 1964. These lesions are well-demarcated, hyperpigmented macules or papules with atrophic depression and were commonly sighted on shins of the tibia with bilateral asymmetrical distribution and rarely seen on arms, thighs and abdomen. The incidence of DD ranges from 0.2 to 55%. It has been frequently associated with microangiopathic complications of diabetes such as nephropathy, retinopathy and polyneuropathy. Although the exact mechanism of occurrence is unknown, it may be related to impaired wound healing due to decreased blood flow, local thermal trauma or local subcutaneous nerve degeneration. Diagnosis is made by clinical examination and the differential diagnosis includes stasis dermatitis, early lesion of necrobiosis lipoidica and purpuric dermatitis. Prevention of dermopathy lesions includes optimized glucose control. No active treatment is recommended or proven effective and DD is known to resolve on its own as time passes. Modified collagen and high glycerine-based lotion have shown marked improvement in skin color changes due to diabetic dermopathy. Diabetic dermopathy is known to have a strong association with microangiopathic complications; the presence of such lesions must raise strong suspicion and prompt investigation for severe underlying pathology. Enhanced scrutinized glycemic control in diabetic dermatopathy patients can even lead to abatement in further progression to microvascular complications and improved long-term patient outcomes.Keywords: diabetic dermopathy, diabetes mellitus, pretibial patches, cutaneous lesions in diabetics, microvascular diseaseNaik PPFarrukh SNDove Medical Pressarticlediabetic dermopathydiabetes mellituspretibial patchescutaneous lesions in diabeticsmicrovascular diseaseSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 13, Pp 4823-4827 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	diabetic dermopathy diabetes mellitus pretibial patches cutaneous lesions in diabetics microvascular disease Specialties of internal medicine RC581-951
spellingShingle	diabetic dermopathy diabetes mellitus pretibial patches cutaneous lesions in diabetics microvascular disease Specialties of internal medicine RC581-951 Naik PP Farrukh SN Clinical Significance of Diabetic Dermatopathy
description	Piyu Parth Naik,1 Syed Nadir Farrukh2 1Department of Dermatology, Saudi-German Hospitals & Clinics, Dubai, United Arab Emirates; 2Department of Internal Medicine, Adam-Vital Hospital, Dubai, United Arab EmiratesCorrespondence: Piyu Parth NaikDepartment of Dermatology, Saudi-German Hospitals & Clinics, Hessa Street 331 West, Al Barsha 3, Exit 36 Sheikh Zayed Road, Opposite of American School, Dubai, United Arab EmiratesTel +971562173323Email drpiyu85@gmail.comAbstract: Diabetic dermopathy is a cutaneous manifestation commonly seen in diabetes patients and was initially described by Melin in 1964. These lesions are well-demarcated, hyperpigmented macules or papules with atrophic depression and were commonly sighted on shins of the tibia with bilateral asymmetrical distribution and rarely seen on arms, thighs and abdomen. The incidence of DD ranges from 0.2 to 55%. It has been frequently associated with microangiopathic complications of diabetes such as nephropathy, retinopathy and polyneuropathy. Although the exact mechanism of occurrence is unknown, it may be related to impaired wound healing due to decreased blood flow, local thermal trauma or local subcutaneous nerve degeneration. Diagnosis is made by clinical examination and the differential diagnosis includes stasis dermatitis, early lesion of necrobiosis lipoidica and purpuric dermatitis. Prevention of dermopathy lesions includes optimized glucose control. No active treatment is recommended or proven effective and DD is known to resolve on its own as time passes. Modified collagen and high glycerine-based lotion have shown marked improvement in skin color changes due to diabetic dermopathy. Diabetic dermopathy is known to have a strong association with microangiopathic complications; the presence of such lesions must raise strong suspicion and prompt investigation for severe underlying pathology. Enhanced scrutinized glycemic control in diabetic dermatopathy patients can even lead to abatement in further progression to microvascular complications and improved long-term patient outcomes.Keywords: diabetic dermopathy, diabetes mellitus, pretibial patches, cutaneous lesions in diabetics, microvascular disease
format	article
author	Naik PP Farrukh SN
author_facet	Naik PP Farrukh SN
author_sort	Naik PP
title	Clinical Significance of Diabetic Dermatopathy
title_short	Clinical Significance of Diabetic Dermatopathy
title_full	Clinical Significance of Diabetic Dermatopathy
title_fullStr	Clinical Significance of Diabetic Dermatopathy
title_full_unstemmed	Clinical Significance of Diabetic Dermatopathy
title_sort	clinical significance of diabetic dermatopathy
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/e618e7f8bb8441179999e52b6f56e729
work_keys_str_mv	AT naikpp clinicalsignificanceofdiabeticdermatopathy AT farrukhsn clinicalsignificanceofdiabeticdermatopathy
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Clinical Significance of Diabetic Dermatopathy

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