Nanoparticles as biochemical sensors

Afaf El-Ansary, Layla M FaddahBiochemistry Department, Science College, and Pharmacology Department, Pharmacy College, King Saud University, Riyadh, Saudi ArabiaAbstract: There is little doubt that nanoparticles offer real and new opportunities in many fields, such as biomedicine and materials scien...

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Autores principales:	Afaf El-Ansary, Layla M Faddah
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Medical technology R855-855.5 Chemical technology TP1-1185
Acceso en línea:	https://doaj.org/article/e61c5964c1fd4bd89ba4dad9b57b790e
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spelling	oai:doaj.org-article:e61c5964c1fd4bd89ba4dad9b57b790e2021-12-02T07:51:23ZNanoparticles as biochemical sensors1177-8903https://doaj.org/article/e61c5964c1fd4bd89ba4dad9b57b790e2010-09-01T00:00:00Zhttp://www.dovepress.com/nanoparticles-as-biochemical-sensors-a5359https://doaj.org/toc/1177-8903Afaf El-Ansary, Layla M FaddahBiochemistry Department, Science College, and Pharmacology Department, Pharmacy College, King Saud University, Riyadh, Saudi ArabiaAbstract: There is little doubt that nanoparticles offer real and new opportunities in many fields, such as biomedicine and materials science. Such particles are small enough to enter almost all areas of the body, including cells and organelles, potentially leading to new approaches in nanomedicine. Sensors for small molecules of biochemical interest are of critical importance. This review is an attempt to trace the use of nanomaterials in biochemical sensor design. The possibility of using nanoparticles functionalized with antibodies as markers for proteins will be elucidated. Moreover, capabilities and applications for nanoparticles based on gold, silver, magnetic, and semiconductor materials (quantum dots), used in optical (absorbance, luminescence, surface enhanced Raman spectroscopy, surface plasmon resonance), electrochemical, and mass-sensitive sensors will be highlighted. The unique ability of nanosensors to improve the analysis of biochemical fluids is discussed either through considering the use of nanoparticles for in vitro molecular diagnosis, or in the biological/biochemical analysis for in vivo interaction with the human body.Keywords: nanoparticles, quantum dots, nanomedicine, biochemical sensors, antibodies, in vivo, in vivo Afaf El-AnsaryLayla M FaddahDove Medical PressarticleMedical technologyR855-855.5Chemical technologyTP1-1185ENNanotechnology, Science and Applications, Vol 2010, Iss default, Pp 65-76 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medical technology R855-855.5 Chemical technology TP1-1185
spellingShingle	Medical technology R855-855.5 Chemical technology TP1-1185 Afaf El-Ansary Layla M Faddah Nanoparticles as biochemical sensors
description	Afaf El-Ansary, Layla M FaddahBiochemistry Department, Science College, and Pharmacology Department, Pharmacy College, King Saud University, Riyadh, Saudi ArabiaAbstract: There is little doubt that nanoparticles offer real and new opportunities in many fields, such as biomedicine and materials science. Such particles are small enough to enter almost all areas of the body, including cells and organelles, potentially leading to new approaches in nanomedicine. Sensors for small molecules of biochemical interest are of critical importance. This review is an attempt to trace the use of nanomaterials in biochemical sensor design. The possibility of using nanoparticles functionalized with antibodies as markers for proteins will be elucidated. Moreover, capabilities and applications for nanoparticles based on gold, silver, magnetic, and semiconductor materials (quantum dots), used in optical (absorbance, luminescence, surface enhanced Raman spectroscopy, surface plasmon resonance), electrochemical, and mass-sensitive sensors will be highlighted. The unique ability of nanosensors to improve the analysis of biochemical fluids is discussed either through considering the use of nanoparticles for in vitro molecular diagnosis, or in the biological/biochemical analysis for in vivo interaction with the human body.Keywords: nanoparticles, quantum dots, nanomedicine, biochemical sensors, antibodies, in vivo, in vivo
format	article
author	Afaf El-Ansary Layla M Faddah
author_facet	Afaf El-Ansary Layla M Faddah
author_sort	Afaf El-Ansary
title	Nanoparticles as biochemical sensors
title_short	Nanoparticles as biochemical sensors
title_full	Nanoparticles as biochemical sensors
title_fullStr	Nanoparticles as biochemical sensors
title_full_unstemmed	Nanoparticles as biochemical sensors
title_sort	nanoparticles as biochemical sensors
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/e61c5964c1fd4bd89ba4dad9b57b790e
work_keys_str_mv	AT afafelansary nanoparticlesasbiochemicalsensors AT laylamfaddah nanoparticlesasbiochemicalsensors
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Nanoparticles as biochemical sensors

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