Nitric oxide mediated transcriptional modulation enhances plant adaptive responses to arsenic stress

Abstract Arsenic (As) contamination in rice leads to yield decline and causes carcinogenic risk to human health. Although the role of nitric oxide (NO) in reducing As toxicity is known, NO-mediated genetic modulation in the plant during arsenic toxicity has not yet been established. We analyzed the...

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Autores principales:	Pradyumna Kumar Singh, Yuvraj Indoliya, Abhisekh Singh Chauhan, Surendra Pratap Singh, Amit Pal Singh, Sanjay Dwivedi, Rudra Deo Tripathi, Debasis Chakrabarty
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e61ed86ac9db4e44bb4a1422ad1c53cb
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spelling	oai:doaj.org-article:e61ed86ac9db4e44bb4a1422ad1c53cb2021-12-02T15:06:21ZNitric oxide mediated transcriptional modulation enhances plant adaptive responses to arsenic stress10.1038/s41598-017-03923-22045-2322https://doaj.org/article/e61ed86ac9db4e44bb4a1422ad1c53cb2017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-03923-2https://doaj.org/toc/2045-2322Abstract Arsenic (As) contamination in rice leads to yield decline and causes carcinogenic risk to human health. Although the role of nitric oxide (NO) in reducing As toxicity is known, NO-mediated genetic modulation in the plant during arsenic toxicity has not yet been established. We analyzed the key components of NO metabolism and the correlations between NO interaction and arsenic stress using rice as a relevant model plant. Illumina sequencing was used to investigate the NO-mediated genome-wide temporal transcriptomic modulation in rice root upon AsIII exposure during 12 days (d) of the growth period. Sodium nitroprusside (SNP) was used as NO donor. SNP supplementation resulted in marked decrease in ROS, cell death and As accumulation during AsIII stress. NO was found to modulate metal transporters particularly NIP, NRAMP, ABC and iron transporters, stress related genes such as CytP450, GSTs, GRXs, TFs, amino acid, hormone(s), signaling and secondary metabolism genes involved in As detoxification. We detected NO-mediated change in jasmonic acid (JA) content during AsIII stress. The study infers that NO reduces AsIII toxicity through modulating regulatory networks involved in As detoxification and JA biosynthesis.Pradyumna Kumar SinghYuvraj IndoliyaAbhisekh Singh ChauhanSurendra Pratap SinghAmit Pal SinghSanjay DwivediRudra Deo TripathiDebasis ChakrabartyNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Pradyumna Kumar Singh Yuvraj Indoliya Abhisekh Singh Chauhan Surendra Pratap Singh Amit Pal Singh Sanjay Dwivedi Rudra Deo Tripathi Debasis Chakrabarty Nitric oxide mediated transcriptional modulation enhances plant adaptive responses to arsenic stress
description	Abstract Arsenic (As) contamination in rice leads to yield decline and causes carcinogenic risk to human health. Although the role of nitric oxide (NO) in reducing As toxicity is known, NO-mediated genetic modulation in the plant during arsenic toxicity has not yet been established. We analyzed the key components of NO metabolism and the correlations between NO interaction and arsenic stress using rice as a relevant model plant. Illumina sequencing was used to investigate the NO-mediated genome-wide temporal transcriptomic modulation in rice root upon AsIII exposure during 12 days (d) of the growth period. Sodium nitroprusside (SNP) was used as NO donor. SNP supplementation resulted in marked decrease in ROS, cell death and As accumulation during AsIII stress. NO was found to modulate metal transporters particularly NIP, NRAMP, ABC and iron transporters, stress related genes such as CytP450, GSTs, GRXs, TFs, amino acid, hormone(s), signaling and secondary metabolism genes involved in As detoxification. We detected NO-mediated change in jasmonic acid (JA) content during AsIII stress. The study infers that NO reduces AsIII toxicity through modulating regulatory networks involved in As detoxification and JA biosynthesis.
format	article
author	Pradyumna Kumar Singh Yuvraj Indoliya Abhisekh Singh Chauhan Surendra Pratap Singh Amit Pal Singh Sanjay Dwivedi Rudra Deo Tripathi Debasis Chakrabarty
author_facet	Pradyumna Kumar Singh Yuvraj Indoliya Abhisekh Singh Chauhan Surendra Pratap Singh Amit Pal Singh Sanjay Dwivedi Rudra Deo Tripathi Debasis Chakrabarty
author_sort	Pradyumna Kumar Singh
title	Nitric oxide mediated transcriptional modulation enhances plant adaptive responses to arsenic stress
title_short	Nitric oxide mediated transcriptional modulation enhances plant adaptive responses to arsenic stress
title_full	Nitric oxide mediated transcriptional modulation enhances plant adaptive responses to arsenic stress
title_fullStr	Nitric oxide mediated transcriptional modulation enhances plant adaptive responses to arsenic stress
title_full_unstemmed	Nitric oxide mediated transcriptional modulation enhances plant adaptive responses to arsenic stress
title_sort	nitric oxide mediated transcriptional modulation enhances plant adaptive responses to arsenic stress
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e61ed86ac9db4e44bb4a1422ad1c53cb
work_keys_str_mv	AT pradyumnakumarsingh nitricoxidemediatedtranscriptionalmodulationenhancesplantadaptiveresponsestoarsenicstress AT yuvrajindoliya nitricoxidemediatedtranscriptionalmodulationenhancesplantadaptiveresponsestoarsenicstress AT abhisekhsinghchauhan nitricoxidemediatedtranscriptionalmodulationenhancesplantadaptiveresponsestoarsenicstress AT surendrapratapsingh nitricoxidemediatedtranscriptionalmodulationenhancesplantadaptiveresponsestoarsenicstress AT amitpalsingh nitricoxidemediatedtranscriptionalmodulationenhancesplantadaptiveresponsestoarsenicstress AT sanjaydwivedi nitricoxidemediatedtranscriptionalmodulationenhancesplantadaptiveresponsestoarsenicstress AT rudradeotripathi nitricoxidemediatedtranscriptionalmodulationenhancesplantadaptiveresponsestoarsenicstress AT debasischakrabarty nitricoxidemediatedtranscriptionalmodulationenhancesplantadaptiveresponsestoarsenicstress
_version_	1718388485640945664

Nitric oxide mediated transcriptional modulation enhances plant adaptive responses to arsenic stress

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