Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer

Long non-coding RNAs (lncRNA; >200 base pair nucleic acids with little protein-coding capacity) are emerging as potentially important regulators of oncogenesis. Here the authors show tumour suppressive lncRNA sponge function for the protein products of prostate cancer driver genes.

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Detalles Bibliográficos
Autores principales: Zhou Du, Tong Sun, Ezgi Hacisuleyman, Teng Fei, Xiaodong Wang, Myles Brown, John L. Rinn, Mary Gwo-Shu Lee, Yiwen Chen, Philip W. Kantoff, X. Shirley Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/e6283a7c074241628b84636c5a04c964
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Sumario:Long non-coding RNAs (lncRNA; >200 base pair nucleic acids with little protein-coding capacity) are emerging as potentially important regulators of oncogenesis. Here the authors show tumour suppressive lncRNA sponge function for the protein products of prostate cancer driver genes.