Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis

Mycobacterium tuberculosis forms biofilms in vitro, but it is unclear whether biofilms are also formed during infection in vivo. Here, Chakraborty et al. demonstrate the formation of biofilms in animal models of infection and in patients with tuberculosis, and that biofilm formation can contribute t...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Poushali Chakraborty, Sapna Bajeli, Deepak Kaushal, Bishan Dass Radotra, Ashwani Kumar
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e6344464f0fb44cfa9b65724b192dc41
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e6344464f0fb44cfa9b65724b192dc41
record_format	dspace
spelling	oai:doaj.org-article:e6344464f0fb44cfa9b65724b192dc412021-12-02T13:15:00ZBiofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis10.1038/s41467-021-21748-62041-1723https://doaj.org/article/e6344464f0fb44cfa9b65724b192dc412021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21748-6https://doaj.org/toc/2041-1723Mycobacterium tuberculosis forms biofilms in vitro, but it is unclear whether biofilms are also formed during infection in vivo. Here, Chakraborty et al. demonstrate the formation of biofilms in animal models of infection and in patients with tuberculosis, and that biofilm formation can contribute to drug tolerance.Poushali ChakrabortySapna BajeliDeepak KaushalBishan Dass RadotraAshwani KumarNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Poushali Chakraborty Sapna Bajeli Deepak Kaushal Bishan Dass Radotra Ashwani Kumar Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis
description	Mycobacterium tuberculosis forms biofilms in vitro, but it is unclear whether biofilms are also formed during infection in vivo. Here, Chakraborty et al. demonstrate the formation of biofilms in animal models of infection and in patients with tuberculosis, and that biofilm formation can contribute to drug tolerance.
format	article
author	Poushali Chakraborty Sapna Bajeli Deepak Kaushal Bishan Dass Radotra Ashwani Kumar
author_facet	Poushali Chakraborty Sapna Bajeli Deepak Kaushal Bishan Dass Radotra Ashwani Kumar
author_sort	Poushali Chakraborty
title	Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis
title_short	Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis
title_full	Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis
title_fullStr	Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis
title_full_unstemmed	Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis
title_sort	biofilm formation in the lung contributes to virulence and drug tolerance of mycobacterium tuberculosis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e6344464f0fb44cfa9b65724b192dc41
work_keys_str_mv	AT poushalichakraborty biofilmformationinthelungcontributestovirulenceanddrugtoleranceofmycobacteriumtuberculosis AT sapnabajeli biofilmformationinthelungcontributestovirulenceanddrugtoleranceofmycobacteriumtuberculosis AT deepakkaushal biofilmformationinthelungcontributestovirulenceanddrugtoleranceofmycobacteriumtuberculosis AT bishandassradotra biofilmformationinthelungcontributestovirulenceanddrugtoleranceofmycobacteriumtuberculosis AT ashwanikumar biofilmformationinthelungcontributestovirulenceanddrugtoleranceofmycobacteriumtuberculosis
_version_	1718393420054003712

Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis

Ejemplares similares