High throughput resistance profiling of Plasmodium falciparum infections based on custom dual indexing and Illumina next generation sequencing-technology

Abstract Genetic polymorphisms in P. falciparum can be used to indicate the parasite’s susceptibility to antimalarial drugs as well as its geographical origin. Both of these factors are key to monitoring development and spread of antimalarial drug resistance. In this study, we combine multiplex PCR,...

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Autores principales: Sidsel Nag, Marlene D. Dalgaard, Poul-Erik Kofoed, Johan Ursing, Marina Crespo, Lee O’Brien Andersen, Frank Møller Aarestrup, Ole Lund, Michael Alifrangis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e639319d64b942d0836b9370fc6a25d1
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