Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation

It is unclear how the cytoskeleton acts to assist in TGF-β signalling downstream of the receptor. Here, in zebrafish, the authors show that the actin-bundling protein FSCN1 interacts with TGF-β type I receptors ALK 4 and 5, enabling actin filament mediated vesicle trafficking and endoderm formation....

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Autores principales:	Zhaoting Liu, Guozhu Ning, Ranran Xu, Yu Cao, Anming Meng, Qiang Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e63bec7aa7c14c579fd97a93bc75d09f
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spelling	oai:doaj.org-article:e63bec7aa7c14c579fd97a93bc75d09f2021-12-02T16:57:02ZFscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation10.1038/ncomms126032041-1723https://doaj.org/article/e63bec7aa7c14c579fd97a93bc75d09f2016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12603https://doaj.org/toc/2041-1723It is unclear how the cytoskeleton acts to assist in TGF-β signalling downstream of the receptor. Here, in zebrafish, the authors show that the actin-bundling protein FSCN1 interacts with TGF-β type I receptors ALK 4 and 5, enabling actin filament mediated vesicle trafficking and endoderm formation.Zhaoting LiuGuozhu NingRanran XuYu CaoAnming MengQiang WangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhaoting Liu Guozhu Ning Ranran Xu Yu Cao Anming Meng Qiang Wang Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation
description	It is unclear how the cytoskeleton acts to assist in TGF-β signalling downstream of the receptor. Here, in zebrafish, the authors show that the actin-bundling protein FSCN1 interacts with TGF-β type I receptors ALK 4 and 5, enabling actin filament mediated vesicle trafficking and endoderm formation.
format	article
author	Zhaoting Liu Guozhu Ning Ranran Xu Yu Cao Anming Meng Qiang Wang
author_facet	Zhaoting Liu Guozhu Ning Ranran Xu Yu Cao Anming Meng Qiang Wang
author_sort	Zhaoting Liu
title	Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation
title_short	Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation
title_full	Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation
title_fullStr	Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation
title_full_unstemmed	Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation
title_sort	fscn1 is required for the trafficking of tgf-β family type i receptors during endoderm formation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/e63bec7aa7c14c579fd97a93bc75d09f
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Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation

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