Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis

Mammalian eggs require a single sperm for viable fertilization, and cortical granule exocytosis prevents additional sperm binding. Vogt et al. image at single granule resolution to document that cortical granule anchoring in the cortex ensures proper trafficking, exocytosis and polyspermy block.

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Autores principales:	Edgar-John Vogt, Keizo Tokuhiro, Min Guo, Ryan Dale, Guanghui Yang, Seung-Wook Shin, Maria Jimenez Movilla, Hari Shroff, Jurrien Dean
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e6424900b9c54c2f9956c43155b7d5da
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spelling	oai:doaj.org-article:e6424900b9c54c2f9956c43155b7d5da2021-12-02T14:35:37ZAnchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis10.1038/s41467-019-10171-72041-1723https://doaj.org/article/e6424900b9c54c2f9956c43155b7d5da2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10171-7https://doaj.org/toc/2041-1723Mammalian eggs require a single sperm for viable fertilization, and cortical granule exocytosis prevents additional sperm binding. Vogt et al. image at single granule resolution to document that cortical granule anchoring in the cortex ensures proper trafficking, exocytosis and polyspermy block.Edgar-John VogtKeizo TokuhiroMin GuoRyan DaleGuanghui YangSeung-Wook ShinMaria Jimenez MovillaHari ShroffJurrien DeanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Edgar-John Vogt Keizo Tokuhiro Min Guo Ryan Dale Guanghui Yang Seung-Wook Shin Maria Jimenez Movilla Hari Shroff Jurrien Dean Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis
description	Mammalian eggs require a single sperm for viable fertilization, and cortical granule exocytosis prevents additional sperm binding. Vogt et al. image at single granule resolution to document that cortical granule anchoring in the cortex ensures proper trafficking, exocytosis and polyspermy block.
format	article
author	Edgar-John Vogt Keizo Tokuhiro Min Guo Ryan Dale Guanghui Yang Seung-Wook Shin Maria Jimenez Movilla Hari Shroff Jurrien Dean
author_facet	Edgar-John Vogt Keizo Tokuhiro Min Guo Ryan Dale Guanghui Yang Seung-Wook Shin Maria Jimenez Movilla Hari Shroff Jurrien Dean
author_sort	Edgar-John Vogt
title	Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis
title_short	Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis
title_full	Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis
title_fullStr	Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis
title_full_unstemmed	Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis
title_sort	anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/e6424900b9c54c2f9956c43155b7d5da
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Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis

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