Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis
Mammalian eggs require a single sperm for viable fertilization, and cortical granule exocytosis prevents additional sperm binding. Vogt et al. image at single granule resolution to document that cortical granule anchoring in the cortex ensures proper trafficking, exocytosis and polyspermy block.
Guardado en:
Autores principales: | Edgar-John Vogt, Keizo Tokuhiro, Min Guo, Ryan Dale, Guanghui Yang, Seung-Wook Shin, Maria Jimenez Movilla, Hari Shroff, Jurrien Dean |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e6424900b9c54c2f9956c43155b7d5da |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Author Correction: Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis
por: Edgar-John Vogt, et al.
Publicado: (2019) -
Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice
por: Seung-Wook Shin, et al.
Publicado: (2017) -
Visualization of cytolytic T cell differentiation and granule exocytosis with T cells from mice expressing active fluorescent granzyme B.
por: Pierre Mouchacca, et al.
Publicado: (2013) -
CLIC4 regulates apical exocytosis and renal tube luminogenesis through retromer- and actin-mediated endocytic trafficking
por: Szu-Yi Chou, et al.
Publicado: (2016) -
A novel function of Noc2 in agonist-induced intracellular Ca2+ increase during zymogen-granule exocytosis in pancreatic acinar cells.
por: Sho Ogata, et al.
Publicado: (2012)