REST regulates the cell cycle for cardiac development and regeneration

The mechanisms regulating cardiomyocyte proliferation during development and cardiac regeneration are incompletely understood. The authors show that the transcription factor REST regulates cardiomyocyte proliferation by binding and repressing the cell cycle inhibitor p21.

Guardado en:
Detalles Bibliográficos
Autores principales: Donghong Zhang, Yidong Wang, Pengfei Lu, Ping Wang, Xinchun Yuan, Jianyun Yan, Chenleng Cai, Ching-Pin Chang, Deyou Zheng, Bingruo Wu, Bin Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/e644a613cf9c426ab48c288f78e91a5e
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:The mechanisms regulating cardiomyocyte proliferation during development and cardiac regeneration are incompletely understood. The authors show that the transcription factor REST regulates cardiomyocyte proliferation by binding and repressing the cell cycle inhibitor p21.