Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma

Several genes, PLOD1, GLT25D1, and KIF22, are identified as potential prognostic markers for LSCC development. In addition, lncRNA–mRNA pairs related to LSCC were explored, and 6 DEGs (MUC21, CEACAM1, FUT7, PADI1, PPL, and ARHGAP40) and 7 DE-lncRNAs (ANKRD20A5P, C21orf15, CYP4F35P, XLOC_I2_003881, X...

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Autores principales: Wang Junguo, Liu Dingding, Gu Yajun, Zhou Han, Li Hui, Shen Xiaohui, Qian Xiaoyun
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Lenguaje:EN
Publicado: De Gruyter 2021
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Acceso en línea:https://doaj.org/article/e648a3de248e413b9a7f1493f31345fd
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spelling oai:doaj.org-article:e648a3de248e413b9a7f1493f31345fd2021-12-05T14:10:41ZPotential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma2391-541210.1515/biol-2021-0052https://doaj.org/article/e648a3de248e413b9a7f1493f31345fd2021-06-01T00:00:00Zhttps://doi.org/10.1515/biol-2021-0052https://doaj.org/toc/2391-5412Several genes, PLOD1, GLT25D1, and KIF22, are identified as potential prognostic markers for LSCC development. In addition, lncRNA–mRNA pairs related to LSCC were explored, and 6 DEGs (MUC21, CEACAM1, FUT7, PADI1, PPL, and ARHGAP40) and 7 DE-lncRNAs (ANKRD20A5P, C21orf15, CYP4F35P, XLOC_I2_003881, XLOC_I2_011146, XLOC_006053, and LOC100506027) were validated to be abnormally expressed in LSCC tissue.Wang JunguoLiu DingdingGu YajunZhou HanLi HuiShen XiaohuiQian XiaoyunDe Gruyterarticlelaryngeal squamous cell carcinomadifferential expressionco-expression analysislncrna–mrnaprognosisBiology (General)QH301-705.5ENOpen Life Sciences, Vol 16, Iss 1, Pp 544-557 (2021)
institution DOAJ
collection DOAJ
language EN
topic laryngeal squamous cell carcinoma
differential expression
co-expression analysis
lncrna–mrna
prognosis
Biology (General)
QH301-705.5
spellingShingle laryngeal squamous cell carcinoma
differential expression
co-expression analysis
lncrna–mrna
prognosis
Biology (General)
QH301-705.5
Wang Junguo
Liu Dingding
Gu Yajun
Zhou Han
Li Hui
Shen Xiaohui
Qian Xiaoyun
Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma
description Several genes, PLOD1, GLT25D1, and KIF22, are identified as potential prognostic markers for LSCC development. In addition, lncRNA–mRNA pairs related to LSCC were explored, and 6 DEGs (MUC21, CEACAM1, FUT7, PADI1, PPL, and ARHGAP40) and 7 DE-lncRNAs (ANKRD20A5P, C21orf15, CYP4F35P, XLOC_I2_003881, XLOC_I2_011146, XLOC_006053, and LOC100506027) were validated to be abnormally expressed in LSCC tissue.
format article
author Wang Junguo
Liu Dingding
Gu Yajun
Zhou Han
Li Hui
Shen Xiaohui
Qian Xiaoyun
author_facet Wang Junguo
Liu Dingding
Gu Yajun
Zhou Han
Li Hui
Shen Xiaohui
Qian Xiaoyun
author_sort Wang Junguo
title Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma
title_short Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma
title_full Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma
title_fullStr Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma
title_full_unstemmed Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma
title_sort potential prognostic markers and significant lncrna–mrna co-expression pairs in laryngeal squamous cell carcinoma
publisher De Gruyter
publishDate 2021
url https://doaj.org/article/e648a3de248e413b9a7f1493f31345fd
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AT guyajun potentialprognosticmarkersandsignificantlncrnamrnacoexpressionpairsinlaryngealsquamouscellcarcinoma
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