Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma
Several genes, PLOD1, GLT25D1, and KIF22, are identified as potential prognostic markers for LSCC development. In addition, lncRNA–mRNA pairs related to LSCC were explored, and 6 DEGs (MUC21, CEACAM1, FUT7, PADI1, PPL, and ARHGAP40) and 7 DE-lncRNAs (ANKRD20A5P, C21orf15, CYP4F35P, XLOC_I2_003881, X...
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De Gruyter
2021
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oai:doaj.org-article:e648a3de248e413b9a7f1493f31345fd2021-12-05T14:10:41ZPotential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma2391-541210.1515/biol-2021-0052https://doaj.org/article/e648a3de248e413b9a7f1493f31345fd2021-06-01T00:00:00Zhttps://doi.org/10.1515/biol-2021-0052https://doaj.org/toc/2391-5412Several genes, PLOD1, GLT25D1, and KIF22, are identified as potential prognostic markers for LSCC development. In addition, lncRNA–mRNA pairs related to LSCC were explored, and 6 DEGs (MUC21, CEACAM1, FUT7, PADI1, PPL, and ARHGAP40) and 7 DE-lncRNAs (ANKRD20A5P, C21orf15, CYP4F35P, XLOC_I2_003881, XLOC_I2_011146, XLOC_006053, and LOC100506027) were validated to be abnormally expressed in LSCC tissue.Wang JunguoLiu DingdingGu YajunZhou HanLi HuiShen XiaohuiQian XiaoyunDe Gruyterarticlelaryngeal squamous cell carcinomadifferential expressionco-expression analysislncrna–mrnaprognosisBiology (General)QH301-705.5ENOpen Life Sciences, Vol 16, Iss 1, Pp 544-557 (2021) |
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laryngeal squamous cell carcinoma differential expression co-expression analysis lncrna–mrna prognosis Biology (General) QH301-705.5 |
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laryngeal squamous cell carcinoma differential expression co-expression analysis lncrna–mrna prognosis Biology (General) QH301-705.5 Wang Junguo Liu Dingding Gu Yajun Zhou Han Li Hui Shen Xiaohui Qian Xiaoyun Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma |
description |
Several genes, PLOD1, GLT25D1, and KIF22, are identified as potential prognostic markers for LSCC development. In addition, lncRNA–mRNA pairs related to LSCC were explored, and 6 DEGs (MUC21, CEACAM1, FUT7, PADI1, PPL, and ARHGAP40) and 7 DE-lncRNAs (ANKRD20A5P, C21orf15, CYP4F35P, XLOC_I2_003881, XLOC_I2_011146, XLOC_006053, and LOC100506027) were validated to be abnormally expressed in LSCC tissue. |
format |
article |
author |
Wang Junguo Liu Dingding Gu Yajun Zhou Han Li Hui Shen Xiaohui Qian Xiaoyun |
author_facet |
Wang Junguo Liu Dingding Gu Yajun Zhou Han Li Hui Shen Xiaohui Qian Xiaoyun |
author_sort |
Wang Junguo |
title |
Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma |
title_short |
Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma |
title_full |
Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma |
title_fullStr |
Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma |
title_full_unstemmed |
Potential prognostic markers and significant lncRNA–mRNA co-expression pairs in laryngeal squamous cell carcinoma |
title_sort |
potential prognostic markers and significant lncrna–mrna co-expression pairs in laryngeal squamous cell carcinoma |
publisher |
De Gruyter |
publishDate |
2021 |
url |
https://doaj.org/article/e648a3de248e413b9a7f1493f31345fd |
work_keys_str_mv |
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