Outcome of penetrating keratoplasty in corneal ulcer: a single-center experience

Mohammad Reza Sedghipour, Rana Sorkhabi, Abdollah Shenasi, Hassan DehghanDepartment of Ophthalmology, Tabriz University of Medical Sciences, Tabriz, IranBackground: Corneal ulcers often lead to scarring and astigmatism, and significant loss of vision is a common consequence.Objective: To determine t...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sedghipour MR, Sorkhabi R, Shenasi A, Dehghan H
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/e649930aac3b456abee410db900985b5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e649930aac3b456abee410db900985b5
record_format	dspace
spelling	oai:doaj.org-article:e649930aac3b456abee410db900985b52021-12-02T03:49:59ZOutcome of penetrating keratoplasty in corneal ulcer: a single-center experience1177-54671177-5483https://doaj.org/article/e649930aac3b456abee410db900985b52011-09-01T00:00:00Zhttp://www.dovepress.com/outcome-of-penetrating-keratoplasty-in-corneal-ulcer-a-single-center-e-a8212https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Mohammad Reza Sedghipour, Rana Sorkhabi, Abdollah Shenasi, Hassan DehghanDepartment of Ophthalmology, Tabriz University of Medical Sciences, Tabriz, IranBackground: Corneal ulcers often lead to scarring and astigmatism, and significant loss of vision is a common consequence.Objective: To determine the rate of graft rejection, one of the most serious concerns with this procedure, and to evaluate the recovery of visual function in those patients for whom the operation was successful.Methods: We describe a retrospective study of 33 corneal ulcer patients undergoing penetrating keratoplasty (PK) at the Tabriz Nikookari Eye Hospital.Results: Mean age of the patients was 44 &plusmn; 14 years. Most common risk factors for active keratitis were trauma, dry eye, and malnutrition. Culture-positive results included bacterial keratitis (n = 15) and fungal keratitis (n = 5). Perforation was a significant risk factor for therapeutic failure (P &lt; 0.05). Age or gender had no statistically significant effects on the PK outcome (P &gt; 0.05). Postoperative visual acuity had a significant association with preoperative visual acuity (P &lt; 0.01). Graft rejection rate (27.2%) was similar to that reported in the literature.Conclusion: Although lamellar keratoplasty has recently been established, there are practical reasons for continuing the use of PK in centers such as ours, with due attention to the requirement for topical immunosuppression to diminish the rate of graft rejection and antimicrobial treatment to prevent postoperative infection.Keywords: keratitis, ulcerative, graft rejection, perforation&nbsp;Sedghipour MRSorkhabi RShenasi ADehghan HDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 1265-1268 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Sedghipour MR Sorkhabi R Shenasi A Dehghan H Outcome of penetrating keratoplasty in corneal ulcer: a single-center experience
description	Mohammad Reza Sedghipour, Rana Sorkhabi, Abdollah Shenasi, Hassan DehghanDepartment of Ophthalmology, Tabriz University of Medical Sciences, Tabriz, IranBackground: Corneal ulcers often lead to scarring and astigmatism, and significant loss of vision is a common consequence.Objective: To determine the rate of graft rejection, one of the most serious concerns with this procedure, and to evaluate the recovery of visual function in those patients for whom the operation was successful.Methods: We describe a retrospective study of 33 corneal ulcer patients undergoing penetrating keratoplasty (PK) at the Tabriz Nikookari Eye Hospital.Results: Mean age of the patients was 44 &plusmn; 14 years. Most common risk factors for active keratitis were trauma, dry eye, and malnutrition. Culture-positive results included bacterial keratitis (n = 15) and fungal keratitis (n = 5). Perforation was a significant risk factor for therapeutic failure (P &lt; 0.05). Age or gender had no statistically significant effects on the PK outcome (P &gt; 0.05). Postoperative visual acuity had a significant association with preoperative visual acuity (P &lt; 0.01). Graft rejection rate (27.2%) was similar to that reported in the literature.Conclusion: Although lamellar keratoplasty has recently been established, there are practical reasons for continuing the use of PK in centers such as ours, with due attention to the requirement for topical immunosuppression to diminish the rate of graft rejection and antimicrobial treatment to prevent postoperative infection.Keywords: keratitis, ulcerative, graft rejection, perforation&nbsp;
format	article
author	Sedghipour MR Sorkhabi R Shenasi A Dehghan H
author_facet	Sedghipour MR Sorkhabi R Shenasi A Dehghan H
author_sort	Sedghipour MR
title	Outcome of penetrating keratoplasty in corneal ulcer: a single-center experience
title_short	Outcome of penetrating keratoplasty in corneal ulcer: a single-center experience
title_full	Outcome of penetrating keratoplasty in corneal ulcer: a single-center experience
title_fullStr	Outcome of penetrating keratoplasty in corneal ulcer: a single-center experience
title_full_unstemmed	Outcome of penetrating keratoplasty in corneal ulcer: a single-center experience
title_sort	outcome of penetrating keratoplasty in corneal ulcer: a single-center experience
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/e649930aac3b456abee410db900985b5
work_keys_str_mv	AT sedghipourmr outcomeofpenetratingkeratoplastyincornealulcerasinglecenterexperience AT sorkhabir outcomeofpenetratingkeratoplastyincornealulcerasinglecenterexperience AT shenasia outcomeofpenetratingkeratoplastyincornealulcerasinglecenterexperience AT dehghanh outcomeofpenetratingkeratoplastyincornealulcerasinglecenterexperience
_version_	1718401618515329024

Outcome of penetrating keratoplasty in corneal ulcer: a single-center experience

Ejemplares similares