Ammonium Formate-Pd/C as a New Reducing System for 1,2,4-Oxadiazoles. Synthesis of Guanidine Derivatives and Reductive Rearrangement to Quinazolin-4-Ones with Potential Anti-Diabetic Activity
1,2,4-Oxadiazole is a heterocycle with wide reactivity and many useful applications. The reactive O-N bond is usually reduced using molecular hydrogen to obtain amidine derivatives. NH<sub>4</sub>CO<sub>2</sub>H-Pd/C is here demonstrated as a new system for the O-N reduction,...
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Main Authors: | Paola Marzullo, Sonya Vasto, Silvestre Buscemi, Andrea Pace, Domenico Nuzzo, Antonio Palumbo Piccionello |
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Format: | article |
Language: | EN |
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MDPI AG
2021
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Online Access: | https://doaj.org/article/e64d262621b6435ab975ad4d9c74eaab |
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