Influence of feeding on serum canine pancreatic lipase immunoreactivity concentrations

Jörg M Steiner, Craig G Ruaux, David A Williams Gastrointestinal Laboratory, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA Abstract: Measurement of serum concentration of pancreatic lipase immunoreactivity (PLI) has been sho...

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Autores principales:	Steiner JM, Ruaux CG, Williams DA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/e6633810fd3e45f1a41622713105e519
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spelling	oai:doaj.org-article:e6633810fd3e45f1a41622713105e5192021-12-02T06:33:25ZInfluence of feeding on serum canine pancreatic lipase immunoreactivity concentrations2230-2034https://doaj.org/article/e6633810fd3e45f1a41622713105e5192014-10-01T00:00:00Zhttp://www.dovepress.com/influence-of-feeding-on-serum-canine-pancreatic-lipase-immunoreactivit-peer-reviewed-article-VMRRhttps://doaj.org/toc/2230-2034 Jörg M Steiner, Craig G Ruaux, David A Williams Gastrointestinal Laboratory, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA Abstract: Measurement of serum concentration of pancreatic lipase immunoreactivity (PLI) has been shown to be highly specific for exocrine pancreatic function and sensitive for the diagnosis of canine pancreatitis. Currently, it is recommended that food be withheld for at least 12 hours before collecting a blood sample for analysis from dogs. However, it is unknown whether feeding has any influence on serum canine PLI concentration. Thus, the goal of this study was to evaluate the influence of feeding on serum canine PLI concentrations in healthy dogs. Food was withheld from eight healthy adult Beagle dogs for at least 17 hours and a baseline serum sample (0 minutes) was collected. Dogs were fed and serum samples were collected at 15, 30, 45, 60, 75, 90, 105, 150, 180, 210, 240, 300, 360, 420, and 480 minutes. There was no significant difference in serum canine PLI concentrations at any time after feeding (P=0.131). We conclude that feeding has no significant influence on serum canine PLI concentrations. Keywords: dog, pancreatic function, pancreatitis, biomarker, diagnostic testSteiner JMRuaux CGWilliams DADove Medical PressarticleVeterinary medicineSF600-1100ENVeterinary Medicine: Research and Reports, Vol 2014, Iss default, Pp 139-142 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Veterinary medicine SF600-1100
spellingShingle	Veterinary medicine SF600-1100 Steiner JM Ruaux CG Williams DA Influence of feeding on serum canine pancreatic lipase immunoreactivity concentrations
description	Jörg M Steiner, Craig G Ruaux, David A Williams Gastrointestinal Laboratory, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA Abstract: Measurement of serum concentration of pancreatic lipase immunoreactivity (PLI) has been shown to be highly specific for exocrine pancreatic function and sensitive for the diagnosis of canine pancreatitis. Currently, it is recommended that food be withheld for at least 12 hours before collecting a blood sample for analysis from dogs. However, it is unknown whether feeding has any influence on serum canine PLI concentration. Thus, the goal of this study was to evaluate the influence of feeding on serum canine PLI concentrations in healthy dogs. Food was withheld from eight healthy adult Beagle dogs for at least 17 hours and a baseline serum sample (0 minutes) was collected. Dogs were fed and serum samples were collected at 15, 30, 45, 60, 75, 90, 105, 150, 180, 210, 240, 300, 360, 420, and 480 minutes. There was no significant difference in serum canine PLI concentrations at any time after feeding (P=0.131). We conclude that feeding has no significant influence on serum canine PLI concentrations. Keywords: dog, pancreatic function, pancreatitis, biomarker, diagnostic test
format	article
author	Steiner JM Ruaux CG Williams DA
author_facet	Steiner JM Ruaux CG Williams DA
author_sort	Steiner JM
title	Influence of feeding on serum canine pancreatic lipase immunoreactivity concentrations
title_short	Influence of feeding on serum canine pancreatic lipase immunoreactivity concentrations
title_full	Influence of feeding on serum canine pancreatic lipase immunoreactivity concentrations
title_fullStr	Influence of feeding on serum canine pancreatic lipase immunoreactivity concentrations
title_full_unstemmed	Influence of feeding on serum canine pancreatic lipase immunoreactivity concentrations
title_sort	influence of feeding on serum canine pancreatic lipase immunoreactivity concentrations
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/e6633810fd3e45f1a41622713105e519
work_keys_str_mv	AT steinerjm influenceoffeedingonserumcaninepancreaticlipaseimmunoreactivityconcentrations AT ruauxcg influenceoffeedingonserumcaninepancreaticlipaseimmunoreactivityconcentrations AT williamsda influenceoffeedingonserumcaninepancreaticlipaseimmunoreactivityconcentrations
_version_	1718399907841179648

Influence of feeding on serum canine pancreatic lipase immunoreactivity concentrations

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