Biosynthesis of fragin is controlled by a novel quorum sensing signal

Fragin is a diazeniumdiolate metabolite with antifungal activity, produced by some bacteria. Here, Jenul et al. show that metal chelation is the molecular basis of fragin’s antifungal activity, and that a gene cluster directing fragin biosynthesis is also involved in the synthesis of a signal molecu...

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Bibliographic Details
Main Authors: Christian Jenul, Simon Sieber, Christophe Daeppen, Anugraha Mathew, Martina Lardi, Gabriella Pessi, Dominic Hoepfner, Markus Neuburger, Anthony Linden, Karl Gademann, Leo Eberl
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/e667f4b8d5a8496998a5b838679cb854
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