Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport

Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport

Activation of brown adipose tissue (BAT) reduces the development of atherosclerosis in animal models. Here the authors show that BAT activation also increases reverse cholesterol transport and turnover of high-density lipoprotein, which likely contributes to the anti-atherosclerotic effect of BAT ac...

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Autores principales: Alexander Bartelt, Clara John, Nicola Schaltenberg, Jimmy F. P. Berbée, Anna Worthmann, M. Lisa Cherradi, Christian Schlein, Julia Piepenburg, Mariëtte R. Boon, Franz Rinninger, Markus Heine, Klaus Toedter, Andreas Niemeier, Stefan K. Nilsson, Markus Fischer, Sander L. Wijers, Wouter van Marken Lichtenbelt, Ludger Scheja, Patrick C. N. Rensen, Joerg Heeren
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
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Acceso en línea:https://doaj.org/article/e668c41f6e524c119524d541ecdad6f7
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Sumario:Activation of brown adipose tissue (BAT) reduces the development of atherosclerosis in animal models. Here the authors show that BAT activation also increases reverse cholesterol transport and turnover of high-density lipoprotein, which likely contributes to the anti-atherosclerotic effect of BAT activation.

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