Differential and Common Signatures of miRNA Expression and Methylation in Childhood Central Nervous System Malignancies: An Experimental and Computational Approach

Epigenetic modifications are considered of utmost significance for tumor ontogenesis and progression. Especially, it has been found that miRNA expression, as well as DNA methylation plays a significant role in central nervous system tumors during childhood. A total of 49 resected brain tumors from c...

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Bibliographic Details
Main Authors: George I. Lambrou, Myrto Poulou, Krinio Giannikou, Marios Themistocleous, Apostolos Zaravinos, Maria Braoudaki
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/e6699fccef764898a623cf366ab6f6bb
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