Multi-reporter selection for the design of active and more specific zinc-finger nucleases for genome editing
Zinc finger nucleases have an established role in genome editing. Here, the authors report a strategy for identifying zinc finger nucleases that discriminate between desired targets and provide genome-wide specificity.
Guardado en:
Autores principales: | Benjamin L. Oakes, Danny F. Xia, Elizabeth F. Rowland, Denise J. Xu, Irina Ankoudinova, Jennifer S. Borchardt, Lei Zhang, Patrick Li, Jeffrey C. Miller, Edward J. Rebar, Marcus B. Noyes |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e66bba0eeef149b0809ce032052bdf58 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Diversifying the structure of zinc finger nucleases for high-precision genome editing
por: David E. Paschon, et al.
Publicado: (2019) -
Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases.
por: Craig B Wilen, et al.
Publicado: (2011) -
Efficient immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases.
por: Tatiana Flisikowska, et al.
Publicado: (2011) -
Synthetic chimeric nucleases function for efficient genome editing
por: R. M. Liu, et al.
Publicado: (2019) -
Zinc Finger Proteins in Neuro-Related Diseases Progression
por: Siyuan Bu, et al.
Publicado: (2021)