24-Hour Profiles of 11-Oxygenated C19 Steroids and Δ5-Steroid Sulfates during Oral and Continuous Subcutaneous Glucocorticoids in 21-Hydroxylase Deficiency
BackgroundOptimal management of androgen excess in 21-hydroxylase deficiency (21OHD) remains challenging. 11-oxygenated-C19 steroids (11-oxyandrogens) have emerged as promising biomarkers of disease control, but data regarding their response to treatment are lacking.ObjectiveTo compare the dynamic r...
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Main Authors: | Adina F. Turcu, Ashwini Mallappa, Aikaterini A. Nella, Xuan Chen, Lili Zhao, Aya T. Nanba, James Brian Byrd, Richard J. Auchus, Deborah P. Merke |
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Format: | article |
Language: | EN |
Published: |
Frontiers Media S.A.
2021
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Online Access: | https://doaj.org/article/e678b04d9d664e889f9b3bec448def53 |
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