Camouflaging bacteria by wrapping with cell membranes
The use of engineered bacteria for biomedical applications is limited by side effects such as inflammatory response. Here the authors engineer cell membrane coated bacteria as in vivo tumor imaging agents, and show that these generate a lower inflammatory response and reduced macrophage clearance.
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Nature Portfolio
2019
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oai:doaj.org-article:e6795b3878514a098385a3a4a86f74612021-12-02T15:35:05ZCamouflaging bacteria by wrapping with cell membranes10.1038/s41467-019-11390-82041-1723https://doaj.org/article/e6795b3878514a098385a3a4a86f74612019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11390-8https://doaj.org/toc/2041-1723The use of engineered bacteria for biomedical applications is limited by side effects such as inflammatory response. Here the authors engineer cell membrane coated bacteria as in vivo tumor imaging agents, and show that these generate a lower inflammatory response and reduced macrophage clearance.Zhenping CaoShanshan ChengXinyue WangYan PangJinyao LiuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
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Science Q Zhenping Cao Shanshan Cheng Xinyue Wang Yan Pang Jinyao Liu Camouflaging bacteria by wrapping with cell membranes |
description |
The use of engineered bacteria for biomedical applications is limited by side effects such as inflammatory response. Here the authors engineer cell membrane coated bacteria as in vivo tumor imaging agents, and show that these generate a lower inflammatory response and reduced macrophage clearance. |
format |
article |
author |
Zhenping Cao Shanshan Cheng Xinyue Wang Yan Pang Jinyao Liu |
author_facet |
Zhenping Cao Shanshan Cheng Xinyue Wang Yan Pang Jinyao Liu |
author_sort |
Zhenping Cao |
title |
Camouflaging bacteria by wrapping with cell membranes |
title_short |
Camouflaging bacteria by wrapping with cell membranes |
title_full |
Camouflaging bacteria by wrapping with cell membranes |
title_fullStr |
Camouflaging bacteria by wrapping with cell membranes |
title_full_unstemmed |
Camouflaging bacteria by wrapping with cell membranes |
title_sort |
camouflaging bacteria by wrapping with cell membranes |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/e6795b3878514a098385a3a4a86f7461 |
work_keys_str_mv |
AT zhenpingcao camouflagingbacteriabywrappingwithcellmembranes AT shanshancheng camouflagingbacteriabywrappingwithcellmembranes AT xinyuewang camouflagingbacteriabywrappingwithcellmembranes AT yanpang camouflagingbacteriabywrappingwithcellmembranes AT jinyaoliu camouflagingbacteriabywrappingwithcellmembranes |
_version_ |
1718386691721396224 |