Camouflaging bacteria by wrapping with cell membranes

The use of engineered bacteria for biomedical applications is limited by side effects such as inflammatory response. Here the authors engineer cell membrane coated bacteria as in vivo tumor imaging agents, and show that these generate a lower inflammatory response and reduced macrophage clearance.

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Autores principales: Zhenping Cao, Shanshan Cheng, Xinyue Wang, Yan Pang, Jinyao Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
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Acceso en línea:https://doaj.org/article/e6795b3878514a098385a3a4a86f7461
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spelling oai:doaj.org-article:e6795b3878514a098385a3a4a86f74612021-12-02T15:35:05ZCamouflaging bacteria by wrapping with cell membranes10.1038/s41467-019-11390-82041-1723https://doaj.org/article/e6795b3878514a098385a3a4a86f74612019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11390-8https://doaj.org/toc/2041-1723The use of engineered bacteria for biomedical applications is limited by side effects such as inflammatory response. Here the authors engineer cell membrane coated bacteria as in vivo tumor imaging agents, and show that these generate a lower inflammatory response and reduced macrophage clearance.Zhenping CaoShanshan ChengXinyue WangYan PangJinyao LiuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zhenping Cao
Shanshan Cheng
Xinyue Wang
Yan Pang
Jinyao Liu
Camouflaging bacteria by wrapping with cell membranes
description The use of engineered bacteria for biomedical applications is limited by side effects such as inflammatory response. Here the authors engineer cell membrane coated bacteria as in vivo tumor imaging agents, and show that these generate a lower inflammatory response and reduced macrophage clearance.
format article
author Zhenping Cao
Shanshan Cheng
Xinyue Wang
Yan Pang
Jinyao Liu
author_facet Zhenping Cao
Shanshan Cheng
Xinyue Wang
Yan Pang
Jinyao Liu
author_sort Zhenping Cao
title Camouflaging bacteria by wrapping with cell membranes
title_short Camouflaging bacteria by wrapping with cell membranes
title_full Camouflaging bacteria by wrapping with cell membranes
title_fullStr Camouflaging bacteria by wrapping with cell membranes
title_full_unstemmed Camouflaging bacteria by wrapping with cell membranes
title_sort camouflaging bacteria by wrapping with cell membranes
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/e6795b3878514a098385a3a4a86f7461
work_keys_str_mv AT zhenpingcao camouflagingbacteriabywrappingwithcellmembranes
AT shanshancheng camouflagingbacteriabywrappingwithcellmembranes
AT xinyuewang camouflagingbacteriabywrappingwithcellmembranes
AT yanpang camouflagingbacteriabywrappingwithcellmembranes
AT jinyaoliu camouflagingbacteriabywrappingwithcellmembranes
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