Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome: clinical perspectives

Priya Bajgai, Deeksha Katoch, Mangat Ram Dogra, Ramandeep Singh Advanced Eye Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India Abstract: Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome typically affects young, healthy individuals. Des...

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Autores principales: Bajgai P, Katoch D, Dogra MR, Singh R
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Lenguaje:EN
Publicado: Dove Medical Press 2017
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spelling oai:doaj.org-article:e6860ceb275c4d06a4f333181820f3f62021-12-02T08:37:15ZIdiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome: clinical perspectives1177-5483https://doaj.org/article/e6860ceb275c4d06a4f333181820f3f62017-10-01T00:00:00Zhttps://www.dovepress.com/idiopathic-retinal-vasculitis-aneurysms-and-neuroretinitis-irvan-syndr-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Priya Bajgai, Deeksha Katoch, Mangat Ram Dogra, Ramandeep Singh Advanced Eye Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India Abstract: Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome typically affects young, healthy individuals. Despite the dramatic fundus appearance seen in this syndrome, these patients are usually asymptomatic. The syndrome includes peculiar vascular abnormalities in the form of multiple aneurysmal dilatations seen along retinal arterioles and optic nerve-head arterioles, which are best appreciated on fluorescein angiography. Neuroretinitis and retinal vasculitis are seen in all patients, and manifested by staining of the optic nerve head and diffuse leakage from vessels, mainly arterioles, on fluorescein angiography. The devastating vision-threatening outcomes of this syndrome include exudative retinopathy and extensive peripheral retinal nonperfusion areas, which can eventually lead to neovascularization. This review summarizes current knowledge on the variable clinical aspects of this disease, highlighting diagnostic and treatment strategies. Keywords: IRVAN, aneurysmal dilatation, neuroretinitis, panretinal photocoagulationBajgai PKatoch DDogra MRSingh RDove Medical PressarticleIRVANAneurysmal dilatationNeuroretinitispanretinal photocoagulationOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 11, Pp 1805-1817 (2017)
institution DOAJ
collection DOAJ
language EN
topic IRVAN
Aneurysmal dilatation
Neuroretinitis
panretinal photocoagulation
Ophthalmology
RE1-994
spellingShingle IRVAN
Aneurysmal dilatation
Neuroretinitis
panretinal photocoagulation
Ophthalmology
RE1-994
Bajgai P
Katoch D
Dogra MR
Singh R
Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome: clinical perspectives
description Priya Bajgai, Deeksha Katoch, Mangat Ram Dogra, Ramandeep Singh Advanced Eye Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India Abstract: Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome typically affects young, healthy individuals. Despite the dramatic fundus appearance seen in this syndrome, these patients are usually asymptomatic. The syndrome includes peculiar vascular abnormalities in the form of multiple aneurysmal dilatations seen along retinal arterioles and optic nerve-head arterioles, which are best appreciated on fluorescein angiography. Neuroretinitis and retinal vasculitis are seen in all patients, and manifested by staining of the optic nerve head and diffuse leakage from vessels, mainly arterioles, on fluorescein angiography. The devastating vision-threatening outcomes of this syndrome include exudative retinopathy and extensive peripheral retinal nonperfusion areas, which can eventually lead to neovascularization. This review summarizes current knowledge on the variable clinical aspects of this disease, highlighting diagnostic and treatment strategies. Keywords: IRVAN, aneurysmal dilatation, neuroretinitis, panretinal photocoagulation
format article
author Bajgai P
Katoch D
Dogra MR
Singh R
author_facet Bajgai P
Katoch D
Dogra MR
Singh R
author_sort Bajgai P
title Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome: clinical perspectives
title_short Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome: clinical perspectives
title_full Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome: clinical perspectives
title_fullStr Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome: clinical perspectives
title_full_unstemmed Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome: clinical perspectives
title_sort idiopathic retinal vasculitis, aneurysms, and neuroretinitis (irvan) syndrome: clinical perspectives
publisher Dove Medical Press
publishDate 2017
url https://doaj.org/article/e6860ceb275c4d06a4f333181820f3f6
work_keys_str_mv AT bajgaip idiopathicretinalvasculitisaneurysmsandneuroretinitisirvansyndromeclinicalperspectives
AT katochd idiopathicretinalvasculitisaneurysmsandneuroretinitisirvansyndromeclinicalperspectives
AT dogramr idiopathicretinalvasculitisaneurysmsandneuroretinitisirvansyndromeclinicalperspectives
AT singhr idiopathicretinalvasculitisaneurysmsandneuroretinitisirvansyndromeclinicalperspectives
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