In Vitro Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Amphotericin B against <i>Candida auris</i>

In Vitro Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Amphotericin B against <i>Candida auris</i>

The aims of this study were to characterize the antifungal activity of amphotericin B against <i>Candida auris</i> in a static in vitro system and to evaluate different dosing schedules and MIC scenarios by means of semi-mechanistic pharmacokinetic/pharmacodynamic (PK/PD) modelling and s...

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Bibliographic Details
Main Authors: Unai Caballero, Elena Eraso, Javier Pemán, Guillermo Quindós, Valvanera Vozmediano, Stephan Schmidt, Nerea Jauregizar
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
<i>Candida auris</i>
PK/PD model
amphotericin B
time-kill curves
Pharmacy and materia medica
RS1-441
Online Access:https://doaj.org/article/e69e23bf110b4853b9214d2e5ab68f2e
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