In Vitro Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Amphotericin B against <i>Candida auris</i>

The aims of this study were to characterize the antifungal activity of amphotericin B against <i>Candida auris</i> in a static in vitro system and to evaluate different dosing schedules and MIC scenarios by means of semi-mechanistic pharmacokinetic/pharmacodynamic (PK/PD) modelling and s...

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Auteurs principaux: Unai Caballero, Elena Eraso, Javier Pemán, Guillermo Quindós, Valvanera Vozmediano, Stephan Schmidt, Nerea Jauregizar
Format: article
Langue:EN
Publié: MDPI AG 2021
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Accès en ligne:https://doaj.org/article/e69e23bf110b4853b9214d2e5ab68f2e
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