CRIF1 deficiency suppresses endothelial cell migration via upregulation of RhoGDI2.

Rho GDP-dissociation inhibitor (RhoGDI), a downregulator of Rho family GTPases, prevents nucleotide exchange and membrane association. It is responsible for the activation of Rho GTPases, which regulate a variety of cellular processes, such as migration. Although RhoGDI2 has been identified as a tum...

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Autores principales: Harsha Nagar, Seonhee Kim, Ikjun Lee, Su-Jeong Choi, Shuyu Piao, Byeong Hwa Jeon, Minho Shong, Cuk-Seong Kim
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/e6a8be85a3e04f38bb339e5682a1a1a4
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