CRIF1 deficiency suppresses endothelial cell migration via upregulation of RhoGDI2.
Rho GDP-dissociation inhibitor (RhoGDI), a downregulator of Rho family GTPases, prevents nucleotide exchange and membrane association. It is responsible for the activation of Rho GTPases, which regulate a variety of cellular processes, such as migration. Although RhoGDI2 has been identified as a tum...
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Autores principales: | Harsha Nagar, Seonhee Kim, Ikjun Lee, Su-Jeong Choi, Shuyu Piao, Byeong Hwa Jeon, Minho Shong, Cuk-Seong Kim |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/e6a8be85a3e04f38bb339e5682a1a1a4 |
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