RELATIONSHIP BETWEEN THE INNATE AND ADAPTIVE IMMUNITY IN INFECTIONS (REVISION OF CLASSIC DOGMA)

Abstract. The mechanisms of the immune system responding to an infection depend on a complex interrelation between the elements of innate and adaptive immunity. The current understanding of how signaling from innate immunity receptors shapes the adaptive immune response against pathogens and how it...

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Autor principal: I. S. Freidlin
Formato: article
Lenguaje:RU
Publicado: Sankt-Peterburg : NIIÈM imeni Pastera 2014
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Acceso en línea:https://doaj.org/article/e6ab0fec16bf4b84ad0640ecc79c9f68
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spelling oai:doaj.org-article:e6ab0fec16bf4b84ad0640ecc79c9f682021-11-22T07:09:45ZRELATIONSHIP BETWEEN THE INNATE AND ADAPTIVE IMMUNITY IN INFECTIONS (REVISION OF CLASSIC DOGMA)2220-76192313-739810.15789/2220-7619-2011-3-199-206https://doaj.org/article/e6ab0fec16bf4b84ad0640ecc79c9f682014-06-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/47https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. The mechanisms of the immune system responding to an infection depend on a complex interrelation between the elements of innate and adaptive immunity. The current understanding of how signaling from innate immunity receptors shapes the adaptive immune response against pathogens and how it looks like the adaptive control of innate immunity are discussed in the article. One of the main problem needed to be highlighted is if adaptive immune cells suppress or activate innate immunity? Several studies yield new light to the question how the adaptive immunity can compensate, suppress and activate innate immunity. The role of inflammatory signals of dendritic cells activation in induction and modulation of adaptive immunity is described. Innate immunity receptors instruct the adaptive immune system on when and how to best respond to a concrete infection.I. S. FreidlinSankt-Peterburg : NIIÈM imeni Pasteraarticleinnate immunityadaptive immunitydcprrtlrsinfectionsInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 1, Iss 3, Pp 199-206 (2014)
institution DOAJ
collection DOAJ
language RU
topic innate immunity
adaptive immunity
dc
prr
tlrs
infections
Infectious and parasitic diseases
RC109-216
spellingShingle innate immunity
adaptive immunity
dc
prr
tlrs
infections
Infectious and parasitic diseases
RC109-216
I. S. Freidlin
RELATIONSHIP BETWEEN THE INNATE AND ADAPTIVE IMMUNITY IN INFECTIONS (REVISION OF CLASSIC DOGMA)
description Abstract. The mechanisms of the immune system responding to an infection depend on a complex interrelation between the elements of innate and adaptive immunity. The current understanding of how signaling from innate immunity receptors shapes the adaptive immune response against pathogens and how it looks like the adaptive control of innate immunity are discussed in the article. One of the main problem needed to be highlighted is if adaptive immune cells suppress or activate innate immunity? Several studies yield new light to the question how the adaptive immunity can compensate, suppress and activate innate immunity. The role of inflammatory signals of dendritic cells activation in induction and modulation of adaptive immunity is described. Innate immunity receptors instruct the adaptive immune system on when and how to best respond to a concrete infection.
format article
author I. S. Freidlin
author_facet I. S. Freidlin
author_sort I. S. Freidlin
title RELATIONSHIP BETWEEN THE INNATE AND ADAPTIVE IMMUNITY IN INFECTIONS (REVISION OF CLASSIC DOGMA)
title_short RELATIONSHIP BETWEEN THE INNATE AND ADAPTIVE IMMUNITY IN INFECTIONS (REVISION OF CLASSIC DOGMA)
title_full RELATIONSHIP BETWEEN THE INNATE AND ADAPTIVE IMMUNITY IN INFECTIONS (REVISION OF CLASSIC DOGMA)
title_fullStr RELATIONSHIP BETWEEN THE INNATE AND ADAPTIVE IMMUNITY IN INFECTIONS (REVISION OF CLASSIC DOGMA)
title_full_unstemmed RELATIONSHIP BETWEEN THE INNATE AND ADAPTIVE IMMUNITY IN INFECTIONS (REVISION OF CLASSIC DOGMA)
title_sort relationship between the innate and adaptive immunity in infections (revision of classic dogma)
publisher Sankt-Peterburg : NIIÈM imeni Pastera
publishDate 2014
url https://doaj.org/article/e6ab0fec16bf4b84ad0640ecc79c9f68
work_keys_str_mv AT isfreidlin relationshipbetweentheinnateandadaptiveimmunityininfectionsrevisionofclassicdogma
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