Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic

T cell responses are known to be essential in the immune response to Ebola virus infection, and the viral glycoprotein is a major antigenic target. Here the authors provide fine detail mapping of T cell antigens and their characterisation in Ebola virus survivor patients.

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Autores principales: T. R. W. Tipton, Y. Hall, J. A. Bore, A. White, L. S. Sibley, C. Sarfas, Y. Yuki, M. Martin, S. Longet, J. Mellors, K. Ewer, S. Günther, M. Carrington, M. K. Kondé, M. W. Carroll
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e6b0735d435f48e18929d44dd2c3bb84
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spelling oai:doaj.org-article:e6b0735d435f48e18929d44dd2c3bb842021-12-02T12:11:11ZCharacterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic10.1038/s41467-021-21411-02041-1723https://doaj.org/article/e6b0735d435f48e18929d44dd2c3bb842021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21411-0https://doaj.org/toc/2041-1723T cell responses are known to be essential in the immune response to Ebola virus infection, and the viral glycoprotein is a major antigenic target. Here the authors provide fine detail mapping of T cell antigens and their characterisation in Ebola virus survivor patients.T. R. W. TiptonY. HallJ. A. BoreA. WhiteL. S. SibleyC. SarfasY. YukiM. MartinS. LongetJ. MellorsK. EwerS. GüntherM. CarringtonM. K. KondéM. W. CarrollNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
T. R. W. Tipton
Y. Hall
J. A. Bore
A. White
L. S. Sibley
C. Sarfas
Y. Yuki
M. Martin
S. Longet
J. Mellors
K. Ewer
S. Günther
M. Carrington
M. K. Kondé
M. W. Carroll
Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic
description T cell responses are known to be essential in the immune response to Ebola virus infection, and the viral glycoprotein is a major antigenic target. Here the authors provide fine detail mapping of T cell antigens and their characterisation in Ebola virus survivor patients.
format article
author T. R. W. Tipton
Y. Hall
J. A. Bore
A. White
L. S. Sibley
C. Sarfas
Y. Yuki
M. Martin
S. Longet
J. Mellors
K. Ewer
S. Günther
M. Carrington
M. K. Kondé
M. W. Carroll
author_facet T. R. W. Tipton
Y. Hall
J. A. Bore
A. White
L. S. Sibley
C. Sarfas
Y. Yuki
M. Martin
S. Longet
J. Mellors
K. Ewer
S. Günther
M. Carrington
M. K. Kondé
M. W. Carroll
author_sort T. R. W. Tipton
title Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic
title_short Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic
title_full Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic
title_fullStr Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic
title_full_unstemmed Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic
title_sort characterisation of the t-cell response to ebola virus glycoprotein amongst survivors of the 2013–16 west africa epidemic
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/e6b0735d435f48e18929d44dd2c3bb84
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