Immunological imprinting of the antibody response in COVID-19 patients

Immunological imprinting of the antibody response in COVID-19 patients

In addition to SARS-CoV-2, other coronaviruses also infect human, but whether consecutive infections cross-modulate the induced immune response is still unclear. Here the authors show that SARS-CoV-2 infection boosts pre-existing responses to other coronaviruses, yet such back-boosting hampers the i...

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Autores principales: Teresa Aydillo, Alexander Rombauts, Daniel Stadlbauer, Sadaf Aslam, Gabriela Abelenda-Alonso, Alba Escalera, Fatima Amanat, Kaijun Jiang, Florian Krammer, Jordi Carratala, Adolfo García-Sastre
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/e6b17aeb12ca4e21a13051d57fbbeb62
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Sumario:In addition to SARS-CoV-2, other coronaviruses also infect human, but whether consecutive infections cross-modulate the induced immune response is still unclear. Here the authors show that SARS-CoV-2 infection boosts pre-existing responses to other coronaviruses, yet such back-boosting hampers the induction of specific antibodies against SARS-CoV-2.

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