Immunological imprinting of the antibody response in COVID-19 patients

In addition to SARS-CoV-2, other coronaviruses also infect human, but whether consecutive infections cross-modulate the induced immune response is still unclear. Here the authors show that SARS-CoV-2 infection boosts pre-existing responses to other coronaviruses, yet such back-boosting hampers the i...

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Autores principales:	Teresa Aydillo, Alexander Rombauts, Daniel Stadlbauer, Sadaf Aslam, Gabriela Abelenda-Alonso, Alba Escalera, Fatima Amanat, Kaijun Jiang, Florian Krammer, Jordi Carratala, Adolfo García-Sastre
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e6b17aeb12ca4e21a13051d57fbbeb62
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spelling	oai:doaj.org-article:e6b17aeb12ca4e21a13051d57fbbeb622021-12-02T17:24:09ZImmunological imprinting of the antibody response in COVID-19 patients10.1038/s41467-021-23977-12041-1723https://doaj.org/article/e6b17aeb12ca4e21a13051d57fbbeb622021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23977-1https://doaj.org/toc/2041-1723In addition to SARS-CoV-2, other coronaviruses also infect human, but whether consecutive infections cross-modulate the induced immune response is still unclear. Here the authors show that SARS-CoV-2 infection boosts pre-existing responses to other coronaviruses, yet such back-boosting hampers the induction of specific antibodies against SARS-CoV-2.Teresa AydilloAlexander RombautsDaniel StadlbauerSadaf AslamGabriela Abelenda-AlonsoAlba EscaleraFatima AmanatKaijun JiangFlorian KrammerJordi CarratalaAdolfo García-SastreNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Teresa Aydillo Alexander Rombauts Daniel Stadlbauer Sadaf Aslam Gabriela Abelenda-Alonso Alba Escalera Fatima Amanat Kaijun Jiang Florian Krammer Jordi Carratala Adolfo García-Sastre Immunological imprinting of the antibody response in COVID-19 patients
description	In addition to SARS-CoV-2, other coronaviruses also infect human, but whether consecutive infections cross-modulate the induced immune response is still unclear. Here the authors show that SARS-CoV-2 infection boosts pre-existing responses to other coronaviruses, yet such back-boosting hampers the induction of specific antibodies against SARS-CoV-2.
format	article
author	Teresa Aydillo Alexander Rombauts Daniel Stadlbauer Sadaf Aslam Gabriela Abelenda-Alonso Alba Escalera Fatima Amanat Kaijun Jiang Florian Krammer Jordi Carratala Adolfo García-Sastre
author_facet	Teresa Aydillo Alexander Rombauts Daniel Stadlbauer Sadaf Aslam Gabriela Abelenda-Alonso Alba Escalera Fatima Amanat Kaijun Jiang Florian Krammer Jordi Carratala Adolfo García-Sastre
author_sort	Teresa Aydillo
title	Immunological imprinting of the antibody response in COVID-19 patients
title_short	Immunological imprinting of the antibody response in COVID-19 patients
title_full	Immunological imprinting of the antibody response in COVID-19 patients
title_fullStr	Immunological imprinting of the antibody response in COVID-19 patients
title_full_unstemmed	Immunological imprinting of the antibody response in COVID-19 patients
title_sort	immunological imprinting of the antibody response in covid-19 patients
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e6b17aeb12ca4e21a13051d57fbbeb62
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Immunological imprinting of the antibody response in COVID-19 patients

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