Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein

Rabies virus (RABV) infection of unvaccinated individuals can be treated with post exposure prophylaxis. Here, Hellert et al. analyze the structure of a broadly neutralizing human antibody in complex with its target domain in the RABV glycoprotein and demonstrate that it blocks the acid-induced conf...

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Auteurs principaux: Jan Hellert, Julian Buchrieser, Florence Larrous, Andrea Minola, Guilherme Dias de Melo, Leah Soriaga, Patrick England, Ahmed Haouz, Amalio Telenti, Olivier Schwartz, Davide Corti, Hervé Bourhy, Félix A. Rey
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/e6bafc79f9814357b005d33b29f35294
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