Dermoscopic Features of Mycosis Fungoides and Its Variants in Patients with Skin of Color: A Retrospective Analysis

Background: Mycosis fungoides (MF) is a cutaneous T-cell lymphoma that disproportionately affects people with skin of color and is difficult to diagnose. Objective: This study characterized the dermoscopic features of MF and its subtypes in patients with skin of color. Methods: Dermoscopic im...

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Autores principales:	Mio Nakamura, Tomas Huerta, Kendrick Williams, Alexandra Hristov, Trilokraj Tejasvi
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2021
Materias:	Cutaneous T-cell lymphoma mycosis fungoides skin of color dermoscopy Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/e6c02242c7134303848497b18085f596
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spelling	oai:doaj.org-article:e6c02242c7134303848497b18085f5962021-11-17T08:27:56ZDermoscopic Features of Mycosis Fungoides and Its Variants in Patients with Skin of Color: A Retrospective Analysis10.5826/dpc.1103a482160-9381https://doaj.org/article/e6c02242c7134303848497b18085f5962021-05-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/1523https://doaj.org/toc/2160-9381 Background: Mycosis fungoides (MF) is a cutaneous T-cell lymphoma that disproportionately affects people with skin of color and is difficult to diagnose. Objective: This study characterized the dermoscopic features of MF and its subtypes in patients with skin of color. Methods: Dermoscopic images of patients with skin of color seen at the cutaneous T-cell lymphoma clinic at Michigan Medicine Dermatology between 2018 and 2019 were reviewed. Specific dermoscopic features were identified and summarized for each subtype of MF. Results: A total of 33 dermoscopic images from 11 patients with skin of color were reviewed. Four patients had classic MF (18 dermoscopic images), 4 had hypopigmented MF (9 dermoscopic images), 1 had folliculotropic MF (4 dermoscopic images), and 2 had verrucous MF (2 dermoscopic images). Classic MF was characterized by striking pigmentary change, thick black lines, white rosettes, and geometric white lines. Hypopigmented MF was characterized by the loss of the patient’s natural pigment network. In folliculotropic MF, follicular plugging and hyperpigmented to violaceous perifollicular halos were observed. In verrucous MF, large, yellow-gray amorphous structures with yellow-gray ridges and comedo-like openings were observed within hyperkeratotic areas. Overall, vessel morphology was difficult to discern on dermoscopy. Conclusions: Dermoscopic features of MF in patients with skin of color are predominantly characterized by striking pigmentary alteration. Vessel morphology is not a reliable diagnostic feature. As patients with MF and skin of color have a worse prognosis than light-skinned individuals, a better understanding of dermoscopic features may aid in early diagnosis and improve outcomes in this group. Mio NakamuraTomas HuertaKendrick WilliamsAlexandra HristovTrilokraj TejasviMattioli1885articleCutaneous T-cell lymphomamycosis fungoidesskin of colordermoscopyDermatologyRL1-803ENDermatology Practical & Conceptual (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Cutaneous T-cell lymphoma mycosis fungoides skin of color dermoscopy Dermatology RL1-803
spellingShingle	Cutaneous T-cell lymphoma mycosis fungoides skin of color dermoscopy Dermatology RL1-803 Mio Nakamura Tomas Huerta Kendrick Williams Alexandra Hristov Trilokraj Tejasvi Dermoscopic Features of Mycosis Fungoides and Its Variants in Patients with Skin of Color: A Retrospective Analysis
description	Background: Mycosis fungoides (MF) is a cutaneous T-cell lymphoma that disproportionately affects people with skin of color and is difficult to diagnose. Objective: This study characterized the dermoscopic features of MF and its subtypes in patients with skin of color. Methods: Dermoscopic images of patients with skin of color seen at the cutaneous T-cell lymphoma clinic at Michigan Medicine Dermatology between 2018 and 2019 were reviewed. Specific dermoscopic features were identified and summarized for each subtype of MF. Results: A total of 33 dermoscopic images from 11 patients with skin of color were reviewed. Four patients had classic MF (18 dermoscopic images), 4 had hypopigmented MF (9 dermoscopic images), 1 had folliculotropic MF (4 dermoscopic images), and 2 had verrucous MF (2 dermoscopic images). Classic MF was characterized by striking pigmentary change, thick black lines, white rosettes, and geometric white lines. Hypopigmented MF was characterized by the loss of the patient’s natural pigment network. In folliculotropic MF, follicular plugging and hyperpigmented to violaceous perifollicular halos were observed. In verrucous MF, large, yellow-gray amorphous structures with yellow-gray ridges and comedo-like openings were observed within hyperkeratotic areas. Overall, vessel morphology was difficult to discern on dermoscopy. Conclusions: Dermoscopic features of MF in patients with skin of color are predominantly characterized by striking pigmentary alteration. Vessel morphology is not a reliable diagnostic feature. As patients with MF and skin of color have a worse prognosis than light-skinned individuals, a better understanding of dermoscopic features may aid in early diagnosis and improve outcomes in this group.
format	article
author	Mio Nakamura Tomas Huerta Kendrick Williams Alexandra Hristov Trilokraj Tejasvi
author_facet	Mio Nakamura Tomas Huerta Kendrick Williams Alexandra Hristov Trilokraj Tejasvi
author_sort	Mio Nakamura
title	Dermoscopic Features of Mycosis Fungoides and Its Variants in Patients with Skin of Color: A Retrospective Analysis
title_short	Dermoscopic Features of Mycosis Fungoides and Its Variants in Patients with Skin of Color: A Retrospective Analysis
title_full	Dermoscopic Features of Mycosis Fungoides and Its Variants in Patients with Skin of Color: A Retrospective Analysis
title_fullStr	Dermoscopic Features of Mycosis Fungoides and Its Variants in Patients with Skin of Color: A Retrospective Analysis
title_full_unstemmed	Dermoscopic Features of Mycosis Fungoides and Its Variants in Patients with Skin of Color: A Retrospective Analysis
title_sort	dermoscopic features of mycosis fungoides and its variants in patients with skin of color: a retrospective analysis
publisher	Mattioli1885
publishDate	2021
url	https://doaj.org/article/e6c02242c7134303848497b18085f596
work_keys_str_mv	AT mionakamura dermoscopicfeaturesofmycosisfungoidesanditsvariantsinpatientswithskinofcoloraretrospectiveanalysis AT tomashuerta dermoscopicfeaturesofmycosisfungoidesanditsvariantsinpatientswithskinofcoloraretrospectiveanalysis AT kendrickwilliams dermoscopicfeaturesofmycosisfungoidesanditsvariantsinpatientswithskinofcoloraretrospectiveanalysis AT alexandrahristov dermoscopicfeaturesofmycosisfungoidesanditsvariantsinpatientswithskinofcoloraretrospectiveanalysis AT trilokrajtejasvi dermoscopicfeaturesofmycosisfungoidesanditsvariantsinpatientswithskinofcoloraretrospectiveanalysis
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Dermoscopic Features of Mycosis Fungoides and Its Variants in Patients with Skin of Color: A Retrospective Analysis

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