A Systematic Review of the Calcium Content of the Normal Human Prostate Gland

Introduction: There is much lack of knowledge concerning most prostatic malfunction, especially the reasons and detailed nature of its pathologies. In spite of advances in medical science, the differential diagnosis of prostatic pathologies has steadily increased in complexity and controversy. A pro...

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Autor principal:	Vladimir Zaichick
Formato:	article
Lenguaje:	EN
Publicado:	Emergency Department of Hospital San Pedro (Logroño, Spain) 2021
Materias:	calcium human prostate normal prostatic tissue biomarkers Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/e6d734c0d45b4bb0a7a718cb5bee3ea4
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spelling	oai:doaj.org-article:e6d734c0d45b4bb0a7a718cb5bee3ea42021-12-02T19:15:00ZA Systematic Review of the Calcium Content of the Normal Human Prostate Gland10.5281/zenodo.44297122695-5075https://doaj.org/article/e6d734c0d45b4bb0a7a718cb5bee3ea42021-01-01T00:00:00Zhttps://doi.org/10.5281/zenodo.4429712https://doaj.org/toc/2695-5075Introduction: There is much lack of knowledge concerning most prostatic malfunction, especially the reasons and detailed nature of its pathologies. In spite of advances in medical science, the differential diagnosis of prostatic pathologies has steadily increased in complexity and controversy. A proposal has been made that prostatic calcium (Ca) content determinations may aid in resolving these issues for prostate disorders and especially as an indicator of its carcinoma risk. As a result many measurements of normal prostatic Ca have been made. Materials and methods: Here we analyze data published concerning Ca prostatic levels in healthy subjects. In all 1911 items in the literature of the years dating back to 1921 were identified in the following databases: PubMed, the Cochrane Library, Scopus, Web of Science and ELSEVIER-EMBASE. This data was subject to an analysis employing both the “range” and “median” of means. In this way the disparate nature of published Ca content of normal prostates was evaluated. From the papers examined, 36 were selected for the objective analysis of data from their 1357 healthy patients.. Results: On a wet mass basis prostatic Ca levels spanned the interval from 73 mg/kg to 1280 mg/kg with 360 mg/kg as the median of their means. It is accepted that the prostatic Ca content is contingent on a wide variety of aspects of the host’s milieu, including androgen levels, zone of human prostate sampled, relative amounts of different types of prostatic tissue studied, Ca content of food and drink, Ca supplement intake, age, and the method of analysis. Conclusions: The data encompassed a wide range of values and the sample was small, hence it is advisable that further studies be performed.Vladimir ZaichickEmergency Department of Hospital San Pedro (Logroño, Spain)articlecalciumhuman prostatenormal prostatic tissuebiomarkersMedicine (General)R5-920ENIberoamerican Journal of Medicine, Vol 3, Iss 1, Pp 85-94 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	calcium human prostate normal prostatic tissue biomarkers Medicine (General) R5-920
spellingShingle	calcium human prostate normal prostatic tissue biomarkers Medicine (General) R5-920 Vladimir Zaichick A Systematic Review of the Calcium Content of the Normal Human Prostate Gland
description	Introduction: There is much lack of knowledge concerning most prostatic malfunction, especially the reasons and detailed nature of its pathologies. In spite of advances in medical science, the differential diagnosis of prostatic pathologies has steadily increased in complexity and controversy. A proposal has been made that prostatic calcium (Ca) content determinations may aid in resolving these issues for prostate disorders and especially as an indicator of its carcinoma risk. As a result many measurements of normal prostatic Ca have been made. Materials and methods: Here we analyze data published concerning Ca prostatic levels in healthy subjects. In all 1911 items in the literature of the years dating back to 1921 were identified in the following databases: PubMed, the Cochrane Library, Scopus, Web of Science and ELSEVIER-EMBASE. This data was subject to an analysis employing both the “range” and “median” of means. In this way the disparate nature of published Ca content of normal prostates was evaluated. From the papers examined, 36 were selected for the objective analysis of data from their 1357 healthy patients.. Results: On a wet mass basis prostatic Ca levels spanned the interval from 73 mg/kg to 1280 mg/kg with 360 mg/kg as the median of their means. It is accepted that the prostatic Ca content is contingent on a wide variety of aspects of the host’s milieu, including androgen levels, zone of human prostate sampled, relative amounts of different types of prostatic tissue studied, Ca content of food and drink, Ca supplement intake, age, and the method of analysis. Conclusions: The data encompassed a wide range of values and the sample was small, hence it is advisable that further studies be performed.
format	article
author	Vladimir Zaichick
author_facet	Vladimir Zaichick
author_sort	Vladimir Zaichick
title	A Systematic Review of the Calcium Content of the Normal Human Prostate Gland
title_short	A Systematic Review of the Calcium Content of the Normal Human Prostate Gland
title_full	A Systematic Review of the Calcium Content of the Normal Human Prostate Gland
title_fullStr	A Systematic Review of the Calcium Content of the Normal Human Prostate Gland
title_full_unstemmed	A Systematic Review of the Calcium Content of the Normal Human Prostate Gland
title_sort	systematic review of the calcium content of the normal human prostate gland
publisher	Emergency Department of Hospital San Pedro (Logroño, Spain)
publishDate	2021
url	https://doaj.org/article/e6d734c0d45b4bb0a7a718cb5bee3ea4
work_keys_str_mv	AT vladimirzaichick asystematicreviewofthecalciumcontentofthenormalhumanprostategland AT vladimirzaichick systematicreviewofthecalciumcontentofthenormalhumanprostategland
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A Systematic Review of the Calcium Content of the Normal Human Prostate Gland

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