Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy
Determination of apical tension, fluidity, and intercellular adhesive forces in an epithelial monolayer are currently disruptive. Here the authors present a method using acoustic force microscopy to measure changes in these parameters upon tight junction structural alterations in a MDCK monolayer.
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Nature Portfolio
2017
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oai:doaj.org-article:e6d9f90d0b7847688bae83343882aa432021-12-02T14:40:34ZApical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy10.1038/s41467-017-01145-82041-1723https://doaj.org/article/e6d9f90d0b7847688bae83343882aa432017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01145-8https://doaj.org/toc/2041-1723Determination of apical tension, fluidity, and intercellular adhesive forces in an epithelial monolayer are currently disruptive. Here the authors present a method using acoustic force microscopy to measure changes in these parameters upon tight junction structural alterations in a MDCK monolayer.Alexander X. Cartagena-RiveraChristina M. Van ItallieJames M. AndersonRichard S. ChadwickNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
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Science Q Alexander X. Cartagena-Rivera Christina M. Van Itallie James M. Anderson Richard S. Chadwick Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy |
description |
Determination of apical tension, fluidity, and intercellular adhesive forces in an epithelial monolayer are currently disruptive. Here the authors present a method using acoustic force microscopy to measure changes in these parameters upon tight junction structural alterations in a MDCK monolayer. |
format |
article |
author |
Alexander X. Cartagena-Rivera Christina M. Van Itallie James M. Anderson Richard S. Chadwick |
author_facet |
Alexander X. Cartagena-Rivera Christina M. Van Itallie James M. Anderson Richard S. Chadwick |
author_sort |
Alexander X. Cartagena-Rivera |
title |
Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy |
title_short |
Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy |
title_full |
Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy |
title_fullStr |
Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy |
title_full_unstemmed |
Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy |
title_sort |
apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/e6d9f90d0b7847688bae83343882aa43 |
work_keys_str_mv |
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_version_ |
1718390269250895872 |