Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy

Determination of apical tension, fluidity, and intercellular adhesive forces in an epithelial monolayer are currently disruptive. Here the authors present a method using acoustic force microscopy to measure changes in these parameters upon tight junction structural alterations in a MDCK monolayer.

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Autores principales: Alexander X. Cartagena-Rivera, Christina M. Van Itallie, James M. Anderson, Richard S. Chadwick
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e6d9f90d0b7847688bae83343882aa43
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spelling oai:doaj.org-article:e6d9f90d0b7847688bae83343882aa432021-12-02T14:40:34ZApical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy10.1038/s41467-017-01145-82041-1723https://doaj.org/article/e6d9f90d0b7847688bae83343882aa432017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01145-8https://doaj.org/toc/2041-1723Determination of apical tension, fluidity, and intercellular adhesive forces in an epithelial monolayer are currently disruptive. Here the authors present a method using acoustic force microscopy to measure changes in these parameters upon tight junction structural alterations in a MDCK monolayer.Alexander X. Cartagena-RiveraChristina M. Van ItallieJames M. AndersonRichard S. ChadwickNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alexander X. Cartagena-Rivera
Christina M. Van Itallie
James M. Anderson
Richard S. Chadwick
Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy
description Determination of apical tension, fluidity, and intercellular adhesive forces in an epithelial monolayer are currently disruptive. Here the authors present a method using acoustic force microscopy to measure changes in these parameters upon tight junction structural alterations in a MDCK monolayer.
format article
author Alexander X. Cartagena-Rivera
Christina M. Van Itallie
James M. Anderson
Richard S. Chadwick
author_facet Alexander X. Cartagena-Rivera
Christina M. Van Itallie
James M. Anderson
Richard S. Chadwick
author_sort Alexander X. Cartagena-Rivera
title Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy
title_short Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy
title_full Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy
title_fullStr Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy
title_full_unstemmed Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy
title_sort apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/e6d9f90d0b7847688bae83343882aa43
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AT christinamvanitallie apicalsurfacesupracellularmechanicalpropertiesinpolarizedepitheliumusingnoninvasiveacousticforcespectroscopy
AT jamesmanderson apicalsurfacesupracellularmechanicalpropertiesinpolarizedepitheliumusingnoninvasiveacousticforcespectroscopy
AT richardschadwick apicalsurfacesupracellularmechanicalpropertiesinpolarizedepitheliumusingnoninvasiveacousticforcespectroscopy
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