The Nrf1 CNC-bZIP protein is regulated by the proteasome and activated by hypoxia.
<h4>Background</h4>Nrf1 (nuclear factor-erythroid 2 p45 subunit-related factor 1) is a transcription factor mediating cellular responses to xenobiotic and pro-oxidant stress. Nrf1 regulates the transcription of many stress-related genes through the electrophile response elements (EpREs)...
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Autores principales: | Nikolai L Chepelev, Joshua D Bennitz, Ting Huang, Skye McBride, William G Willmore |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/e6db0690b6f849baa8c9bca45a792be3 |
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