The Nrf1 CNC-bZIP protein is regulated by the proteasome and activated by hypoxia.

<h4>Background</h4>Nrf1 (nuclear factor-erythroid 2 p45 subunit-related factor 1) is a transcription factor mediating cellular responses to xenobiotic and pro-oxidant stress. Nrf1 regulates the transcription of many stress-related genes through the electrophile response elements (EpREs)...

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Auteurs principaux: Nikolai L Chepelev, Joshua D Bennitz, Ting Huang, Skye McBride, William G Willmore
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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R
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Accès en ligne:https://doaj.org/article/e6db0690b6f849baa8c9bca45a792be3
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