Dissecting the mammary gland one cell at a time

Abstract Dissecting cellular differentiation hierarchies in the mammary gland is a prerequisite for understanding both normal development and malignant transformation during tumorigenesis and tumor cell-of-origin. To achieve these goals, several recent papers utilized single cell RNA-seq and lineage...

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Autores principales:	Simona Cristea, Kornelia Polyak
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e6e11296796045e7af2c5afa46712fe0
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spelling	oai:doaj.org-article:e6e11296796045e7af2c5afa46712fe02021-12-02T17:32:46ZDissecting the mammary gland one cell at a time10.1038/s41467-018-04905-22041-1723https://doaj.org/article/e6e11296796045e7af2c5afa46712fe02018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04905-2https://doaj.org/toc/2041-1723Abstract Dissecting cellular differentiation hierarchies in the mammary gland is a prerequisite for understanding both normal development and malignant transformation during tumorigenesis and tumor cell-of-origin. To achieve these goals, several recent papers utilized single cell RNA-seq and lineage tracing to improve our understanding of the composition of the mammary epithelium at different developmental stages.Simona CristeaKornelia PolyakNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-3 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Simona Cristea Kornelia Polyak Dissecting the mammary gland one cell at a time
description	Abstract Dissecting cellular differentiation hierarchies in the mammary gland is a prerequisite for understanding both normal development and malignant transformation during tumorigenesis and tumor cell-of-origin. To achieve these goals, several recent papers utilized single cell RNA-seq and lineage tracing to improve our understanding of the composition of the mammary epithelium at different developmental stages.
format	article
author	Simona Cristea Kornelia Polyak
author_facet	Simona Cristea Kornelia Polyak
author_sort	Simona Cristea
title	Dissecting the mammary gland one cell at a time
title_short	Dissecting the mammary gland one cell at a time
title_full	Dissecting the mammary gland one cell at a time
title_fullStr	Dissecting the mammary gland one cell at a time
title_full_unstemmed	Dissecting the mammary gland one cell at a time
title_sort	dissecting the mammary gland one cell at a time
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e6e11296796045e7af2c5afa46712fe0
work_keys_str_mv	AT simonacristea dissectingthemammaryglandonecellatatime AT korneliapolyak dissectingthemammaryglandonecellatatime
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Dissecting the mammary gland one cell at a time

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