Incidence and prevalence of vitreomacular traction with and without macular hole in Germany

Jacob Menzler,1 Aljoscha Steffen Neubauer,1,2 Christos Haritoglou,3 Timothy L Jackson4 1Institute for Health- and Pharmacoeconomics/Neubauer Consult, Munich, Germany; 2Private practice, Munich, Germany; 3Herzog Carl Theodor Eye Hospital, Munich, Germany; 4Department of Ophthalmology, Faculty of Lif...

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Autores principales:	Menzler J, Neubauer AS, Haritoglou C, Jackson TL
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Epidemiology vitreous body/*pathology vitreous adhesion/detachment pars plana vitrectomy Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/e6e15c66a8c147c4a43fa250a7fc746c
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spelling	oai:doaj.org-article:e6e15c66a8c147c4a43fa250a7fc746c2021-12-02T04:07:16ZIncidence and prevalence of vitreomacular traction with and without macular hole in Germany1177-5483https://doaj.org/article/e6e15c66a8c147c4a43fa250a7fc746c2019-01-01T00:00:00Zhttps://www.dovepress.com/incidence-and-prevalence-of-vitreomacular-traction-with-and-without-ma-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Jacob Menzler,1 Aljoscha Steffen Neubauer,1,2 Christos Haritoglou,3 Timothy L Jackson4 1Institute for Health- and Pharmacoeconomics/Neubauer Consult, Munich, Germany; 2Private practice, Munich, Germany; 3Herzog Carl Theodor Eye Hospital, Munich, Germany; 4Department of Ophthalmology, Faculty of Life Course Sciences and Medicine, King’s College London, London, UK Purpose: Symptomatic vitreomacular adhesion (sVMA) comprises vitreomacular traction (VMT) and stage 1 and 2 full-thickness macular holes (MHs) associated with vitreomacular adhesion (VMA). We aimed to estimate the incidence and prevalence of sVMA in Germany.Materials and methods: A systematic literature review was conducted to identify the incidence and prevalence of sVMA based on international epidemiologic studies, weighted for study size and then averaged across eligible studies. A second systematic review aimed to estimate the proportion of vitrectomy undertaken for sVMA in Germany. This was combined with the reported number of vitrectomies in Germany in 2016 to estimate the number of patients undergoing vitrectomy for sVMA.Results: The prevalence of sVMA is 1,365 per 100,000 population, with an incidence of 6.96 per 100,000 per year. For Germany, this translates to 1,119,300 cases, with 5,700 new cases reported annually. Analyzing the national hospital statistics, ~2,300 patients undergo vitrectomy due to sVMA in Germany each year, of which about 1,700 patients have VMT.Conclusion: Incidence figures, driven by patients presenting to clinic, are much lower than expected based on population-based studies, suggesting that many patients with sVMA exist outside of the clinic system. Keywords: epidemiology, vitreous body, vitreous pathology, vitreous adhesion, vitreous detachment, pars plana vitrectomy Menzler JNeubauer ASHaritoglou CJackson TLDove Medical PressarticleEpidemiologyvitreous body/*pathologyvitreous adhesion/detachmentpars plana vitrectomyOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 13, Pp 177-188 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Epidemiology vitreous body/*pathology vitreous adhesion/detachment pars plana vitrectomy Ophthalmology RE1-994
spellingShingle	Epidemiology vitreous body/*pathology vitreous adhesion/detachment pars plana vitrectomy Ophthalmology RE1-994 Menzler J Neubauer AS Haritoglou C Jackson TL Incidence and prevalence of vitreomacular traction with and without macular hole in Germany
description	Jacob Menzler,1 Aljoscha Steffen Neubauer,1,2 Christos Haritoglou,3 Timothy L Jackson4 1Institute for Health- and Pharmacoeconomics/Neubauer Consult, Munich, Germany; 2Private practice, Munich, Germany; 3Herzog Carl Theodor Eye Hospital, Munich, Germany; 4Department of Ophthalmology, Faculty of Life Course Sciences and Medicine, King’s College London, London, UK Purpose: Symptomatic vitreomacular adhesion (sVMA) comprises vitreomacular traction (VMT) and stage 1 and 2 full-thickness macular holes (MHs) associated with vitreomacular adhesion (VMA). We aimed to estimate the incidence and prevalence of sVMA in Germany.Materials and methods: A systematic literature review was conducted to identify the incidence and prevalence of sVMA based on international epidemiologic studies, weighted for study size and then averaged across eligible studies. A second systematic review aimed to estimate the proportion of vitrectomy undertaken for sVMA in Germany. This was combined with the reported number of vitrectomies in Germany in 2016 to estimate the number of patients undergoing vitrectomy for sVMA.Results: The prevalence of sVMA is 1,365 per 100,000 population, with an incidence of 6.96 per 100,000 per year. For Germany, this translates to 1,119,300 cases, with 5,700 new cases reported annually. Analyzing the national hospital statistics, ~2,300 patients undergo vitrectomy due to sVMA in Germany each year, of which about 1,700 patients have VMT.Conclusion: Incidence figures, driven by patients presenting to clinic, are much lower than expected based on population-based studies, suggesting that many patients with sVMA exist outside of the clinic system. Keywords: epidemiology, vitreous body, vitreous pathology, vitreous adhesion, vitreous detachment, pars plana vitrectomy
format	article
author	Menzler J Neubauer AS Haritoglou C Jackson TL
author_facet	Menzler J Neubauer AS Haritoglou C Jackson TL
author_sort	Menzler J
title	Incidence and prevalence of vitreomacular traction with and without macular hole in Germany
title_short	Incidence and prevalence of vitreomacular traction with and without macular hole in Germany
title_full	Incidence and prevalence of vitreomacular traction with and without macular hole in Germany
title_fullStr	Incidence and prevalence of vitreomacular traction with and without macular hole in Germany
title_full_unstemmed	Incidence and prevalence of vitreomacular traction with and without macular hole in Germany
title_sort	incidence and prevalence of vitreomacular traction with and without macular hole in germany
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/e6e15c66a8c147c4a43fa250a7fc746c
work_keys_str_mv	AT menzlerj incidenceandprevalenceofvitreomaculartractionwithandwithoutmacularholeingermany AT neubaueras incidenceandprevalenceofvitreomaculartractionwithandwithoutmacularholeingermany AT haritoglouc incidenceandprevalenceofvitreomaculartractionwithandwithoutmacularholeingermany AT jacksontl incidenceandprevalenceofvitreomaculartractionwithandwithoutmacularholeingermany
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Incidence and prevalence of vitreomacular traction with and without macular hole in Germany

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