Imprinted Zeolite Modified Carbon Paste Electrode as a Selective Sensor for Blood Glucose Analysis by Potentiometry

Imprinted zeolite modified carbon paste (carbon paste-IZ) electrode had been developed as a sensor to analyze blood glucose content by potentiometry. The used zeolite was Lynde Type A (LTA) that synthesized with a mole ratio of Na2O, Al2O3, SiO2 and H2O of 4:1:1.8:270, respectively while non-imprint...

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Autores principales:	Miratul Khasanah, Alfa Akustia Widati, Usreg Sri Handajani, Muji Harsini, Bahrotul Ilmiah, Irene Dinda Oktavia
Formato:	article
Lenguaje:	EN
Publicado:	Department of Chemistry, Universitas Gadjah Mada 2020
Materias:	blood glucose carbon paste electrode imprinted zeolite potentiometric sensor Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/e6e2231c1d6141a1949ef88145d893c5
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spelling	oai:doaj.org-article:e6e2231c1d6141a1949ef88145d893c52021-12-02T12:03:36ZImprinted Zeolite Modified Carbon Paste Electrode as a Selective Sensor for Blood Glucose Analysis by Potentiometry1411-94202460-157810.22146/ijc.49820https://doaj.org/article/e6e2231c1d6141a1949ef88145d893c52020-06-01T00:00:00Zhttps://jurnal.ugm.ac.id/ijc/article/view/49820https://doaj.org/toc/1411-9420https://doaj.org/toc/2460-1578Imprinted zeolite modified carbon paste (carbon paste-IZ) electrode had been developed as a sensor to analyze blood glucose content by potentiometry. The used zeolite was Lynde Type A (LTA) that synthesized with a mole ratio of Na2O, Al2O3, SiO2 and H2O of 4:1:1.8:270, respectively while non-imprinted zeolite was prepared with a mole ratio of glucose/Si of 0.0306. Glucose was then extracted from the zeolite framework using hot water (80 °C) to produce imprinted zeolite (IZ). The carbon paste-IZ electrode prepared from activated carbon, paraffin pastilles, and IZ with a mass ratio of 5:4:1 showed the best performance. The modified electrode demonstrated the measurement range of 10–4-10–2 M, the Nernst factor of 29.55 mV/decade, the response time less than 120 s, and the detection limit of 5.62 × 10–5 M. Ascorbic acid, uric acid, urea and creatinine did not interfere on the glucose analysis by potentiometry. Comparison test with spectrophotometry showed an accuracy of (90.7 ± 1.4)% (n = 5), while the application of the electrode to analyze five spiked serum samples showed recovery of (92.2 ± 1.3)% (n = 5). The electrode was stable for up to 9 weeks (168 times usage). Based on its performance, the developed electrode can be applied to analyze glucose in human serum sample and recommended for used in the medical field.Miratul KhasanahAlfa Akustia WidatiUsreg Sri HandajaniMuji HarsiniBahrotul IlmiahIrene Dinda OktaviaDepartment of Chemistry, Universitas Gadjah Madaarticleblood glucosecarbon paste electrodeimprinted zeolitepotentiometric sensorChemistryQD1-999ENIndonesian Journal of Chemistry, Vol 20, Iss 6, Pp 1301-1310 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	blood glucose carbon paste electrode imprinted zeolite potentiometric sensor Chemistry QD1-999
spellingShingle	blood glucose carbon paste electrode imprinted zeolite potentiometric sensor Chemistry QD1-999 Miratul Khasanah Alfa Akustia Widati Usreg Sri Handajani Muji Harsini Bahrotul Ilmiah Irene Dinda Oktavia Imprinted Zeolite Modified Carbon Paste Electrode as a Selective Sensor for Blood Glucose Analysis by Potentiometry
description	Imprinted zeolite modified carbon paste (carbon paste-IZ) electrode had been developed as a sensor to analyze blood glucose content by potentiometry. The used zeolite was Lynde Type A (LTA) that synthesized with a mole ratio of Na2O, Al2O3, SiO2 and H2O of 4:1:1.8:270, respectively while non-imprinted zeolite was prepared with a mole ratio of glucose/Si of 0.0306. Glucose was then extracted from the zeolite framework using hot water (80 °C) to produce imprinted zeolite (IZ). The carbon paste-IZ electrode prepared from activated carbon, paraffin pastilles, and IZ with a mass ratio of 5:4:1 showed the best performance. The modified electrode demonstrated the measurement range of 10–4-10–2 M, the Nernst factor of 29.55 mV/decade, the response time less than 120 s, and the detection limit of 5.62 × 10–5 M. Ascorbic acid, uric acid, urea and creatinine did not interfere on the glucose analysis by potentiometry. Comparison test with spectrophotometry showed an accuracy of (90.7 ± 1.4)% (n = 5), while the application of the electrode to analyze five spiked serum samples showed recovery of (92.2 ± 1.3)% (n = 5). The electrode was stable for up to 9 weeks (168 times usage). Based on its performance, the developed electrode can be applied to analyze glucose in human serum sample and recommended for used in the medical field.
format	article
author	Miratul Khasanah Alfa Akustia Widati Usreg Sri Handajani Muji Harsini Bahrotul Ilmiah Irene Dinda Oktavia
author_facet	Miratul Khasanah Alfa Akustia Widati Usreg Sri Handajani Muji Harsini Bahrotul Ilmiah Irene Dinda Oktavia
author_sort	Miratul Khasanah
title	Imprinted Zeolite Modified Carbon Paste Electrode as a Selective Sensor for Blood Glucose Analysis by Potentiometry
title_short	Imprinted Zeolite Modified Carbon Paste Electrode as a Selective Sensor for Blood Glucose Analysis by Potentiometry
title_full	Imprinted Zeolite Modified Carbon Paste Electrode as a Selective Sensor for Blood Glucose Analysis by Potentiometry
title_fullStr	Imprinted Zeolite Modified Carbon Paste Electrode as a Selective Sensor for Blood Glucose Analysis by Potentiometry
title_full_unstemmed	Imprinted Zeolite Modified Carbon Paste Electrode as a Selective Sensor for Blood Glucose Analysis by Potentiometry
title_sort	imprinted zeolite modified carbon paste electrode as a selective sensor for blood glucose analysis by potentiometry
publisher	Department of Chemistry, Universitas Gadjah Mada
publishDate	2020
url	https://doaj.org/article/e6e2231c1d6141a1949ef88145d893c5
work_keys_str_mv	AT miratulkhasanah imprintedzeolitemodifiedcarbonpasteelectrodeasaselectivesensorforbloodglucoseanalysisbypotentiometry AT alfaakustiawidati imprintedzeolitemodifiedcarbonpasteelectrodeasaselectivesensorforbloodglucoseanalysisbypotentiometry AT usregsrihandajani imprintedzeolitemodifiedcarbonpasteelectrodeasaselectivesensorforbloodglucoseanalysisbypotentiometry AT mujiharsini imprintedzeolitemodifiedcarbonpasteelectrodeasaselectivesensorforbloodglucoseanalysisbypotentiometry AT bahrotulilmiah imprintedzeolitemodifiedcarbonpasteelectrodeasaselectivesensorforbloodglucoseanalysisbypotentiometry AT irenedindaoktavia imprintedzeolitemodifiedcarbonpasteelectrodeasaselectivesensorforbloodglucoseanalysisbypotentiometry
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Imprinted Zeolite Modified Carbon Paste Electrode as a Selective Sensor for Blood Glucose Analysis by Potentiometry

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