Metabolic modelling reveals broad changes in gut microbial metabolism in inflammatory bowel disease patients with dysbiosis
Abstract Inflammatory bowel diseases, such as Crohn’s Disease, are characterised by an altered blood and faecal metabolome, and changes in gut microbiome composition. Here, we present an efficient, scalable, tractable systems biology framework to mechanistically link microbial strains and faecal met...
Guardado en:
Autores principales: | Almut Heinken, Johannes Hertel, Ines Thiele |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e6e483ee5d984df2971eaa7426fe3994 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Altered gut bacterial and metabolic signatures and their interaction in inflammatory bowel disease
por: Guangcai Liang
Publicado: (2021) -
Gut microbial co-abundance networks show specificity in inflammatory bowel disease and obesity
por: Lianmin Chen, et al.
Publicado: (2020) -
Gut Microbiota Dysbiosis Is Associated with Altered Bile Acid Metabolism in Infantile Cholestasis
por: Yizhong Wang, et al.
Publicado: (2019) -
Dysbiosis in Metabolic Genes of the Gut Microbiomes of Patients with an Ileo-anal Pouch Resembles That Observed in Crohn's Disease
por: Vadim Dubinsky, et al.
Publicado: (2021) -
From Network Analysis to Functional Metabolic Modeling of the Human Gut Microbiota
por: Eugen Bauer, et al.
Publicado: (2018)