Time-frequency time-space long short-term memory networks for image classification of histopathological tissue

Abstract Image analysis in histopathology provides insights into the microscopic examination of tissue for disease diagnosis, prognosis, and biomarker discovery. Particularly for cancer research, precise classification of histopathological images is the ultimate objective of the image analysis. Here...

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Autor principal: Tuan D. Pham
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e6e6d54865f14d7988830a92e14f3ebc
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spelling oai:doaj.org-article:e6e6d54865f14d7988830a92e14f3ebc2021-12-02T16:10:37ZTime-frequency time-space long short-term memory networks for image classification of histopathological tissue10.1038/s41598-021-93160-52045-2322https://doaj.org/article/e6e6d54865f14d7988830a92e14f3ebc2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93160-5https://doaj.org/toc/2045-2322Abstract Image analysis in histopathology provides insights into the microscopic examination of tissue for disease diagnosis, prognosis, and biomarker discovery. Particularly for cancer research, precise classification of histopathological images is the ultimate objective of the image analysis. Here, the time-frequency time-space long short-term memory network (TF-TS LSTM) developed for classification of time series is applied for classifying histopathological images. The deep learning is empowered by the use of sequential time-frequency and time-space features extracted from the images. Furthermore, unlike conventional classification practice, a strategy for class modeling is designed to leverage the learning power of the TF-TS LSTM. Tests on several datasets of histopathological images of haematoxylin-and-eosin and immunohistochemistry stains demonstrate the strong capability of the artificial intelligence (AI)-based approach for producing very accurate classification results. The proposed approach has the potential to be an AI tool for robust classification of histopathological images.Tuan D. PhamNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Tuan D. Pham
Time-frequency time-space long short-term memory networks for image classification of histopathological tissue
description Abstract Image analysis in histopathology provides insights into the microscopic examination of tissue for disease diagnosis, prognosis, and biomarker discovery. Particularly for cancer research, precise classification of histopathological images is the ultimate objective of the image analysis. Here, the time-frequency time-space long short-term memory network (TF-TS LSTM) developed for classification of time series is applied for classifying histopathological images. The deep learning is empowered by the use of sequential time-frequency and time-space features extracted from the images. Furthermore, unlike conventional classification practice, a strategy for class modeling is designed to leverage the learning power of the TF-TS LSTM. Tests on several datasets of histopathological images of haematoxylin-and-eosin and immunohistochemistry stains demonstrate the strong capability of the artificial intelligence (AI)-based approach for producing very accurate classification results. The proposed approach has the potential to be an AI tool for robust classification of histopathological images.
format article
author Tuan D. Pham
author_facet Tuan D. Pham
author_sort Tuan D. Pham
title Time-frequency time-space long short-term memory networks for image classification of histopathological tissue
title_short Time-frequency time-space long short-term memory networks for image classification of histopathological tissue
title_full Time-frequency time-space long short-term memory networks for image classification of histopathological tissue
title_fullStr Time-frequency time-space long short-term memory networks for image classification of histopathological tissue
title_full_unstemmed Time-frequency time-space long short-term memory networks for image classification of histopathological tissue
title_sort time-frequency time-space long short-term memory networks for image classification of histopathological tissue
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/e6e6d54865f14d7988830a92e14f3ebc
work_keys_str_mv AT tuandpham timefrequencytimespacelongshorttermmemorynetworksforimageclassificationofhistopathologicaltissue
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