Pho4 Is Essential for Dissemination of <named-content content-type="genus-species">Cryptococcus neoformans</named-content> to the Host Brain by Promoting Phosphate Uptake and Growth at Alkaline pH
ABSTRACT Phosphate acquisition by fungi is regulated by the phosphate-sensing and acquisition (PHO) signaling pathway. Cryptococcus neoformans disseminates from the lung to the brain and is the commonest cause of fungal meningitis worldwide. To investigate the contribution of PHO signaling to crypto...
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Auteurs principaux: | Sophie Lev, Keren Kaufman-Francis, Desmarini Desmarini, Pierre G. Juillard, Cecilia Li, Sebastian A. Stifter, Carl G. Feng, Tania C. Sorrell, Georges E. R. Grau, Yong-Sun Bahn, Julianne T. Djordjevic |
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Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2017
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Accès en ligne: | https://doaj.org/article/e6ebd73772e44c50ab5233ebc0ecbd4b |
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