Quantitative single-cell proteomics as a tool to characterize cellular hierarchies

Single-cell proteomics can provide insights into the molecular basis for cellular heterogeneity. Here, the authors develop a multiplexed single-cell proteomics and computational workflow, and show that their strategy captures the cellular hierarchies in an Acute Myeloid Leukemia culture model.

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Detalles Bibliográficos
Autores principales: Erwin M. Schoof, Benjamin Furtwängler, Nil Üresin, Nicolas Rapin, Simonas Savickas, Coline Gentil, Eric Lechman, Ulrich auf dem Keller, John E. Dick, Bo T. Porse
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e6eed179838c43b99f45da74c1d34042
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