In vitro protease cleavage and computer simulations reveal the HIV-1 capsid maturation pathway
Two competing models—disassembly/reassembly and displacive—have been proposed for how immature spherical HIV virions transform into mature particles with conical cores. Here the authors provide evidence that both disassembly/reassembly and displacive processes occur sequentially during the maturatio...
Guardado en:
Autores principales: | Jiying Ning, Gonca Erdemci-Tandogan, Ernest L. Yufenyuy, Jef Wagner, Benjamin A. Himes, Gongpu Zhao, Christopher Aiken, Roya Zandi, Peijun Zhang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e6fb1da96d5249b4968508b5d2a47b9e |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Protease cleavage leads to formation of mature trimer interface in HIV-1 capsid.
por: Xin Meng, et al.
Publicado: (2012) -
Quenching protein dynamics interferes with HIV capsid maturation
por: Mingzhang Wang, et al.
Publicado: (2017) -
Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site
por: Chuang Liu, et al.
Publicado: (2016) -
Rhesus TRIM5α disrupts the HIV-1 capsid at the inter-hexamer interfaces.
por: Gongpu Zhao, et al.
Publicado: (2011) -
Maturation of the Human Papillomavirus 16 Capsid
por: Giovanni Cardone, et al.
Publicado: (2014)