Prognostic impact of pre-transplant chromosomal aberrations in peripheral blood of patients undergoing unrelated donor hematopoietic cell transplant for acute myeloid leukemia

Prognostic impact of pre-transplant chromosomal aberrations in peripheral blood of patients undergoing unrelated donor hematopoietic cell transplant for acute myeloid leukemia

Abstract To improve risk stratification and treatment decisions for patients with acute myeloid leukemia (AML) undergoing hematopoietic cell transplantation (HCT). We used SNP-array data from the DISCOVeRY-BMT study to detect chromosomal aberrations in pre-HCT peripheral blood (collected 2–4 weeks b...

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Main Authors: Youjin Wang, Weiyin Zhou, Lisa J. McReynolds, Hormuzd A. Katki, Elizabeth A. Griffiths, Swapna Thota, Mitchell J. Machiela, Meredith Yeager, Philip McCarthy, Marcelo Pasquini, Junke Wang, Ezgi Karaesmen, Abbas Rizvi, Leah Preus, Hancong Tang, Yiwen Wang, Loreall Pooler, Xin Sheng, Christopher A. Haiman, David Van Den Berg, Stephen R. Spellman, Tao Wang, Michelle Kuxhausen, Stephen J. Chanock, Stephanie J. Lee, Theresa E. Hahn, Lara E. Sucheston-Campbell, Shahinaz M. Gadalla
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/e700d72e5c1b4de9b3ebf24378046514
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