Efflux Impacts Intracellular Accumulation Only in Actively Growing Bacterial Cells

Efflux Impacts Intracellular Accumulation Only in Actively Growing Bacterial Cells

This study shows that efflux is important for maintaining low intracellular accumulation only in actively growing cells and that envelope permeability is the predominant factor in stationary-phase cells. This conclusion means that (i) antibiotics with intracellular targets may be less effective in...

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Autores principales: Emily E. Whittle, Helen E. McNeil, Eleftheria Trampari, Mark Webber, Tim W. Overton, Jessica M. A. Blair
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/e7078d590ca34faf877a261e8fd24c0f
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