Resolution of pituitary microadenoma after coronavirus disease 2019: a case report

Abstract Background This report describes the case of a patient whose pituitary microadenoma resolved after he contracted coronavirus disease 2019. To our knowledge, this is one of the first reported cases of pituitary tumor resolution due to viral illness. We present this case to further investigat...

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Autores principales:	Salah Raishan, Mohammed Alsabri, Ann Mary Hanna, Matthew Brett
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	COVID-19 Pituitary microadenoma Spontaneous resolution Case report Medicine R
Acceso en línea:	https://doaj.org/article/e70add3c53134790a081efb3497be250
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spelling	oai:doaj.org-article:e70add3c53134790a081efb3497be2502021-11-08T11:13:53ZResolution of pituitary microadenoma after coronavirus disease 2019: a case report10.1186/s13256-021-03127-31752-1947https://doaj.org/article/e70add3c53134790a081efb3497be2502021-11-01T00:00:00Zhttps://doi.org/10.1186/s13256-021-03127-3https://doaj.org/toc/1752-1947Abstract Background This report describes the case of a patient whose pituitary microadenoma resolved after he contracted coronavirus disease 2019. To our knowledge, this is one of the first reported cases of pituitary tumor resolution due to viral illness. We present this case to further investigate the relationship between inflammatory response and tumor remission. Case presentation A 32-year-old man in Yemen presented to the hospital with fever, low blood oxygen saturation, and shortness of breath. The patient was diagnosed with coronavirus disease 2019. Past medical history included pituitary microadenoma that was diagnosed using magnetic resonance imaging and secondary adrenal insufficiency, which was treated with steroids. Due to the severity of coronavirus disease 2019, he was treated with steroids and supportive care. Three months after his initial presentation to the hospital, brain magnetic resonance imaging was performed and compared with past scans. Magnetic resonance imaging revealed changes in the microadenoma, including the disappearance of the hypointense lesion and hyperintense enhancement observed on the previous scan. Conclusions Pituitary adenomas rarely undergo spontaneous resolution. Therefore, we hypothesized that tumor resolution was secondary to an immune response to coronavirus disease 2019.Salah RaishanMohammed AlsabriAnn Mary HannaMatthew BrettBMCarticleCOVID-19Pituitary microadenomaSpontaneous resolutionCase reportMedicineRENJournal of Medical Case Reports, Vol 15, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 Pituitary microadenoma Spontaneous resolution Case report Medicine R
spellingShingle	COVID-19 Pituitary microadenoma Spontaneous resolution Case report Medicine R Salah Raishan Mohammed Alsabri Ann Mary Hanna Matthew Brett Resolution of pituitary microadenoma after coronavirus disease 2019: a case report
description	Abstract Background This report describes the case of a patient whose pituitary microadenoma resolved after he contracted coronavirus disease 2019. To our knowledge, this is one of the first reported cases of pituitary tumor resolution due to viral illness. We present this case to further investigate the relationship between inflammatory response and tumor remission. Case presentation A 32-year-old man in Yemen presented to the hospital with fever, low blood oxygen saturation, and shortness of breath. The patient was diagnosed with coronavirus disease 2019. Past medical history included pituitary microadenoma that was diagnosed using magnetic resonance imaging and secondary adrenal insufficiency, which was treated with steroids. Due to the severity of coronavirus disease 2019, he was treated with steroids and supportive care. Three months after his initial presentation to the hospital, brain magnetic resonance imaging was performed and compared with past scans. Magnetic resonance imaging revealed changes in the microadenoma, including the disappearance of the hypointense lesion and hyperintense enhancement observed on the previous scan. Conclusions Pituitary adenomas rarely undergo spontaneous resolution. Therefore, we hypothesized that tumor resolution was secondary to an immune response to coronavirus disease 2019.
format	article
author	Salah Raishan Mohammed Alsabri Ann Mary Hanna Matthew Brett
author_facet	Salah Raishan Mohammed Alsabri Ann Mary Hanna Matthew Brett
author_sort	Salah Raishan
title	Resolution of pituitary microadenoma after coronavirus disease 2019: a case report
title_short	Resolution of pituitary microadenoma after coronavirus disease 2019: a case report
title_full	Resolution of pituitary microadenoma after coronavirus disease 2019: a case report
title_fullStr	Resolution of pituitary microadenoma after coronavirus disease 2019: a case report
title_full_unstemmed	Resolution of pituitary microadenoma after coronavirus disease 2019: a case report
title_sort	resolution of pituitary microadenoma after coronavirus disease 2019: a case report
publisher	BMC
publishDate	2021
url	https://doaj.org/article/e70add3c53134790a081efb3497be250
work_keys_str_mv	AT salahraishan resolutionofpituitarymicroadenomaaftercoronavirusdisease2019acasereport AT mohammedalsabri resolutionofpituitarymicroadenomaaftercoronavirusdisease2019acasereport AT annmaryhanna resolutionofpituitarymicroadenomaaftercoronavirusdisease2019acasereport AT matthewbrett resolutionofpituitarymicroadenomaaftercoronavirusdisease2019acasereport
_version_	1718442385971609600

Resolution of pituitary microadenoma after coronavirus disease 2019: a case report

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