Synthesis of 1-(2-Methoxybenzyl)-1,10-phenanthrolin-1-ium Bromide from Gandapura Oil

This study describes simple synthetic method to prepare 1-(2-methoxybenzyl)-1,10-phenanthrolin-1-ium bromide from gandapura oil. The salt were synthesized in four steps. Initially, commercial gandapura oil was directly subjected to the alkylation reaction under basic condition using dimethyl sulfate...

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Autores principales:	Muhammad Idham Darussalam Mardjan, Dhina Fitriastuti, Bambang Purwono, Jumina Jumina
Formato:	article
Lenguaje:	EN
Publicado:	University of Brawijaya 2019
Materias:	phenanthroline salt gandapura oil alkylation reduction halogenation and bimolecular nucleophilic substitution Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/e714a72bbd714bab80774ea5df5e20e0
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spelling	oai:doaj.org-article:e714a72bbd714bab80774ea5df5e20e02021-12-02T14:21:46ZSynthesis of 1-(2-Methoxybenzyl)-1,10-phenanthrolin-1-ium Bromide from Gandapura Oil2302-46902302-4690https://doaj.org/article/e714a72bbd714bab80774ea5df5e20e02019-12-01T00:00:00Zhttps://jpacr.ub.ac.id/index.php/jpacr/article/view/484/pdfhttps://doaj.org/toc/2302-4690https://doaj.org/toc/2302-4690This study describes simple synthetic method to prepare 1-(2-methoxybenzyl)-1,10-phenanthrolin-1-ium bromide from gandapura oil. The salt were synthesized in four steps. Initially, commercial gandapura oil was directly subjected to the alkylation reaction under basic condition using dimethyl sulfate to give methyl 2-methxybenzoate in 86% yield. Next, the produced benzoate ester was reduced by LiAlH4 to produce 2-methoxybenzyl alcohol in 67% yield. The treatment of benzyl alcohol with phosphorus tribromide under solvent free condition produced the corresponding benzyl bromide (in 67% yield), which was directly introduced into bimolecular nucleophilic substitution reaction with 1,10-phenantroline monohydrate to finally give the desired product in 63% yield.Muhammad Idham Darussalam MardjanDhina FitriastutiBambang PurwonoJumina JuminaUniversity of Brawijayaarticlephenanthroline saltgandapura oilalkylationreductionhalogenation and bimolecular nucleophilic substitutionChemistryQD1-999ENJournal of Pure and Applied Chemistry Research, Vol 8, Iss 3, Pp 239-244 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	phenanthroline salt gandapura oil alkylation reduction halogenation and bimolecular nucleophilic substitution Chemistry QD1-999
spellingShingle	phenanthroline salt gandapura oil alkylation reduction halogenation and bimolecular nucleophilic substitution Chemistry QD1-999 Muhammad Idham Darussalam Mardjan Dhina Fitriastuti Bambang Purwono Jumina Jumina Synthesis of 1-(2-Methoxybenzyl)-1,10-phenanthrolin-1-ium Bromide from Gandapura Oil
description	This study describes simple synthetic method to prepare 1-(2-methoxybenzyl)-1,10-phenanthrolin-1-ium bromide from gandapura oil. The salt were synthesized in four steps. Initially, commercial gandapura oil was directly subjected to the alkylation reaction under basic condition using dimethyl sulfate to give methyl 2-methxybenzoate in 86% yield. Next, the produced benzoate ester was reduced by LiAlH4 to produce 2-methoxybenzyl alcohol in 67% yield. The treatment of benzyl alcohol with phosphorus tribromide under solvent free condition produced the corresponding benzyl bromide (in 67% yield), which was directly introduced into bimolecular nucleophilic substitution reaction with 1,10-phenantroline monohydrate to finally give the desired product in 63% yield.
format	article
author	Muhammad Idham Darussalam Mardjan Dhina Fitriastuti Bambang Purwono Jumina Jumina
author_facet	Muhammad Idham Darussalam Mardjan Dhina Fitriastuti Bambang Purwono Jumina Jumina
author_sort	Muhammad Idham Darussalam Mardjan
title	Synthesis of 1-(2-Methoxybenzyl)-1,10-phenanthrolin-1-ium Bromide from Gandapura Oil
title_short	Synthesis of 1-(2-Methoxybenzyl)-1,10-phenanthrolin-1-ium Bromide from Gandapura Oil
title_full	Synthesis of 1-(2-Methoxybenzyl)-1,10-phenanthrolin-1-ium Bromide from Gandapura Oil
title_fullStr	Synthesis of 1-(2-Methoxybenzyl)-1,10-phenanthrolin-1-ium Bromide from Gandapura Oil
title_full_unstemmed	Synthesis of 1-(2-Methoxybenzyl)-1,10-phenanthrolin-1-ium Bromide from Gandapura Oil
title_sort	synthesis of 1-(2-methoxybenzyl)-1,10-phenanthrolin-1-ium bromide from gandapura oil
publisher	University of Brawijaya
publishDate	2019
url	https://doaj.org/article/e714a72bbd714bab80774ea5df5e20e0
work_keys_str_mv	AT muhammadidhamdarussalammardjan synthesisof12methoxybenzyl110phenanthrolin1iumbromidefromgandapuraoil AT dhinafitriastuti synthesisof12methoxybenzyl110phenanthrolin1iumbromidefromgandapuraoil AT bambangpurwono synthesisof12methoxybenzyl110phenanthrolin1iumbromidefromgandapuraoil AT juminajumina synthesisof12methoxybenzyl110phenanthrolin1iumbromidefromgandapuraoil
_version_	1718391522018197504

Synthesis of 1-(2-Methoxybenzyl)-1,10-phenanthrolin-1-ium Bromide from Gandapura Oil

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