Portable optical epidural needle-a CMOS-based system solution and its circuit design.

Epidural anesthesia is a common anesthesia method yet up to 10% of procedures fail to provide adequate analgesia. This is usually due to misinterpreting the tactile information derived from the advancing needle through the complex tissue planes. Incorrect placement also can cause dural puncture and...

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Autores principales: Cihun-Siyong Alex Gong, Shih-Pin Lin, M Susan Mandell, Mei-Yung Tsou, Yin Chang, Chien-Kun Ting
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Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/e716e0b1b69f4d0e9f655df6a9ea8a86
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spelling oai:doaj.org-article:e716e0b1b69f4d0e9f655df6a9ea8a862021-11-25T06:03:06ZPortable optical epidural needle-a CMOS-based system solution and its circuit design.1932-620310.1371/journal.pone.0106055https://doaj.org/article/e716e0b1b69f4d0e9f655df6a9ea8a862014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25162150/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Epidural anesthesia is a common anesthesia method yet up to 10% of procedures fail to provide adequate analgesia. This is usually due to misinterpreting the tactile information derived from the advancing needle through the complex tissue planes. Incorrect placement also can cause dural puncture and neural injury. We developed an optic system capable of reliably identifying tissue planes surrounding the epidural space. However the new technology was too large and cumbersome for practical clinical use. We present a miniaturized version of our optic system using chip technology (first generation CMOS-based system) for logic functions. The new system was connected to an alarm that was triggered once the optic properties of the epidural were identified. The aims of this study were to test our miniaturized system in a porcine model and describe the technology to build this new clinical tool. Our system was tested in a porcine model and identified the epidural space in the lumbar, low and high thoracic regions of the spine. The new technology identified the epidural space in all but 1 of 46 attempts. Experimental results from our fabricated integrated circuit and animal study show the new tool has future clinical potential.Cihun-Siyong Alex GongShih-Pin LinM Susan MandellMei-Yung TsouYin ChangChien-Kun TingPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 8, p e106055 (2014)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Cihun-Siyong Alex Gong
Shih-Pin Lin
M Susan Mandell
Mei-Yung Tsou
Yin Chang
Chien-Kun Ting
Portable optical epidural needle-a CMOS-based system solution and its circuit design.
description Epidural anesthesia is a common anesthesia method yet up to 10% of procedures fail to provide adequate analgesia. This is usually due to misinterpreting the tactile information derived from the advancing needle through the complex tissue planes. Incorrect placement also can cause dural puncture and neural injury. We developed an optic system capable of reliably identifying tissue planes surrounding the epidural space. However the new technology was too large and cumbersome for practical clinical use. We present a miniaturized version of our optic system using chip technology (first generation CMOS-based system) for logic functions. The new system was connected to an alarm that was triggered once the optic properties of the epidural were identified. The aims of this study were to test our miniaturized system in a porcine model and describe the technology to build this new clinical tool. Our system was tested in a porcine model and identified the epidural space in the lumbar, low and high thoracic regions of the spine. The new technology identified the epidural space in all but 1 of 46 attempts. Experimental results from our fabricated integrated circuit and animal study show the new tool has future clinical potential.
format article
author Cihun-Siyong Alex Gong
Shih-Pin Lin
M Susan Mandell
Mei-Yung Tsou
Yin Chang
Chien-Kun Ting
author_facet Cihun-Siyong Alex Gong
Shih-Pin Lin
M Susan Mandell
Mei-Yung Tsou
Yin Chang
Chien-Kun Ting
author_sort Cihun-Siyong Alex Gong
title Portable optical epidural needle-a CMOS-based system solution and its circuit design.
title_short Portable optical epidural needle-a CMOS-based system solution and its circuit design.
title_full Portable optical epidural needle-a CMOS-based system solution and its circuit design.
title_fullStr Portable optical epidural needle-a CMOS-based system solution and its circuit design.
title_full_unstemmed Portable optical epidural needle-a CMOS-based system solution and its circuit design.
title_sort portable optical epidural needle-a cmos-based system solution and its circuit design.
publisher Public Library of Science (PLoS)
publishDate 2014
url https://doaj.org/article/e716e0b1b69f4d0e9f655df6a9ea8a86
work_keys_str_mv AT cihunsiyongalexgong portableopticalepiduralneedleacmosbasedsystemsolutionanditscircuitdesign
AT shihpinlin portableopticalepiduralneedleacmosbasedsystemsolutionanditscircuitdesign
AT msusanmandell portableopticalepiduralneedleacmosbasedsystemsolutionanditscircuitdesign
AT meiyungtsou portableopticalepiduralneedleacmosbasedsystemsolutionanditscircuitdesign
AT yinchang portableopticalepiduralneedleacmosbasedsystemsolutionanditscircuitdesign
AT chienkunting portableopticalepiduralneedleacmosbasedsystemsolutionanditscircuitdesign
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