Direct visualization of protease action on collagen triple helical structure.

Direct visualization of protease action on collagen triple helical structure.

Enzymatic processing of extracellular matrix (ECM) macromolecules by matrix metalloproteases (MMPs) is crucial in mediating physiological and pathological cell processes. However, the molecular mechanisms leading to effective physiological enzyme-ECM interactions remain elusive. Only scant informati...

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Autores principales: Gabriel Rosenblum, Philippe E Van den Steen, Sidney R Cohen, Arkady Bitler, David D Brand, Ghislain Opdenakker, Irit Sagi
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/e71aeca16b1d4383a579ce21a040cd4e
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