Association between overactive bladder and pelvic organ mobility as evaluated by dynamic magnetic resonance imaging

Abstract Overactive bladder (OAB) is a prevalent condition, which negatively impacts patients’ quality of life. Pelvic organ prolapse (POP), also prevalent in women, has been recognized as an important etiology of female OAB, although the pathophysiological mechanisms remain controversial. In this s...

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Autores principales:	Kurenai Kinno, Noritoshi Sekido, Yasuharu Takeuchi, Yoshitomo Sawada, Shoutarou Watanabe, Yasukuni Yoshimura
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e71bd7bf859b476088d6b5a2b6152a0b
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spelling	oai:doaj.org-article:e71bd7bf859b476088d6b5a2b6152a0b2021-12-02T14:33:51ZAssociation between overactive bladder and pelvic organ mobility as evaluated by dynamic magnetic resonance imaging10.1038/s41598-021-93143-62045-2322https://doaj.org/article/e71bd7bf859b476088d6b5a2b6152a0b2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93143-6https://doaj.org/toc/2045-2322Abstract Overactive bladder (OAB) is a prevalent condition, which negatively impacts patients’ quality of life. Pelvic organ prolapse (POP), also prevalent in women, has been recognized as an important etiology of female OAB, although the pathophysiological mechanisms remain controversial. In this study, we reviewed findings of dynamic magnetic resonance imaging (dMRI) in 118 patients with POP and investigated the association between dMRI findings, including positions and mobilities of pelvic organs as well as parameters of pelvic organ support and bladder outlet obstruction (urethral kinking), and OAB in order to elucidate the pathophysiology of OAB in patients with POP. Our results showed that compared with non-OAB patients, OAB patients had a significantly higher body mass index, more severe pelvic floor muscle impairment, and more profound supportive defects in the uterine cervix (apical compartment). On the other hand, dMRI parameters showed hardly any significant difference between patients with mild and moderate to severe OAB. These findings may imply that levator ani impairment and defective supports of the apical compartment could be associated with the presence of OAB and that the severity of OAB could be affected by factors other than those related to pelvic organ mobility and support or urethral kinking.Kurenai KinnoNoritoshi SekidoYasuharu TakeuchiYoshitomo SawadaShoutarou WatanabeYasukuni YoshimuraNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kurenai Kinno Noritoshi Sekido Yasuharu Takeuchi Yoshitomo Sawada Shoutarou Watanabe Yasukuni Yoshimura Association between overactive bladder and pelvic organ mobility as evaluated by dynamic magnetic resonance imaging
description	Abstract Overactive bladder (OAB) is a prevalent condition, which negatively impacts patients’ quality of life. Pelvic organ prolapse (POP), also prevalent in women, has been recognized as an important etiology of female OAB, although the pathophysiological mechanisms remain controversial. In this study, we reviewed findings of dynamic magnetic resonance imaging (dMRI) in 118 patients with POP and investigated the association between dMRI findings, including positions and mobilities of pelvic organs as well as parameters of pelvic organ support and bladder outlet obstruction (urethral kinking), and OAB in order to elucidate the pathophysiology of OAB in patients with POP. Our results showed that compared with non-OAB patients, OAB patients had a significantly higher body mass index, more severe pelvic floor muscle impairment, and more profound supportive defects in the uterine cervix (apical compartment). On the other hand, dMRI parameters showed hardly any significant difference between patients with mild and moderate to severe OAB. These findings may imply that levator ani impairment and defective supports of the apical compartment could be associated with the presence of OAB and that the severity of OAB could be affected by factors other than those related to pelvic organ mobility and support or urethral kinking.
format	article
author	Kurenai Kinno Noritoshi Sekido Yasuharu Takeuchi Yoshitomo Sawada Shoutarou Watanabe Yasukuni Yoshimura
author_facet	Kurenai Kinno Noritoshi Sekido Yasuharu Takeuchi Yoshitomo Sawada Shoutarou Watanabe Yasukuni Yoshimura
author_sort	Kurenai Kinno
title	Association between overactive bladder and pelvic organ mobility as evaluated by dynamic magnetic resonance imaging
title_short	Association between overactive bladder and pelvic organ mobility as evaluated by dynamic magnetic resonance imaging
title_full	Association between overactive bladder and pelvic organ mobility as evaluated by dynamic magnetic resonance imaging
title_fullStr	Association between overactive bladder and pelvic organ mobility as evaluated by dynamic magnetic resonance imaging
title_full_unstemmed	Association between overactive bladder and pelvic organ mobility as evaluated by dynamic magnetic resonance imaging
title_sort	association between overactive bladder and pelvic organ mobility as evaluated by dynamic magnetic resonance imaging
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e71bd7bf859b476088d6b5a2b6152a0b
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Association between overactive bladder and pelvic organ mobility as evaluated by dynamic magnetic resonance imaging

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